曲美他嗪治疗扩张型心肌病临床疗效观察

目的 观察曲美他嗪治疗扩张型心肌病的临床效果.方法 将本医院的74例扩张型心肌病患者进行随机化的分组,每组都是37例患者,而且两组患者在患有扩张型心肌病的基础上也有心力衰竭,两组患者分别是分为治疗组以及观察组.对于两组的患者都会给予治疗心力衰竭的药物,但是也存在有不同之处,就是观察组的患者必须给予曲美他嗪,而对照组的可以不给予药物,也可以给予安慰剂,同时观察两组患者,对于患者进行随访,时间大约为6个月.通过对患者的随访观察,观察患者治疗前后两组患者的心力衰竭的加重再住院率,和心功能改善程度以及左心室的射血分数.结果 观察组的37人当中有32人最后的症状得到改善,比开始的时候得到恢复,通过计算,得出扩张型心肌病好转的患者大约为86.49％,但是对照组的情况却不容乐观,仅仅只有25个人得到好转,也就是大约有三分之二的患者情况比原来有所改善,根据统计学的观点,治疗后的两组患者进行对比,差异具有统计学意义（P＜0.05）.结论 曲美他嗪对于扩张型心肌病患者的治疗具有很好的效果,而且对于患者病情的改善具有很大的帮助.

Clinical effect observation of trimetazidine treatment of dilated cardiomyopathy

Objective To observe the trimetazidine treatment of dilated cardiomyopathy clinical Results. Methods 74 cases of the hospital dilated cardiomyopathy patients randomized grouping, all 37 patients in each group, and two groups of patients suffering from dilated cardiomyopathy have heart failure on the basis of the two groups of patients were divided into treatment group and the observation group. For both groups of patients will be given a drug treatment of heart failure, but there are differences, is to the observation group patients must be given trimetazidine, while the control group can not give drugs can also be given a placebo, while were observed for patients followed up for about six months. Through observation of the patient follow-up, patients were observed before and after treatment in patients with heart failure readmission rates increased, and the degree of improvement of cardiac function and left ventricular ejection fraction. Results The 37 individuals among them 32 people last improvement in symptoms, compared with the beginning of time have been restored, by calculating, for a final dilated cardiomyopathy improved about 86.49% of the patients, but the control group, the situation is not optimistic, with only 25 people get better, which is about two-thirds patients has improved over the original, based on a statistical point of view, after treatment, the two groups were compared, The diffevence was statistically significant（P〈O.05）. Conclusion Trimetazidine for dilated cardiomyopathy patients has a good effect, but also for the improvement of the patient＇s condition has great help.