| 武汉地区献血员血清TTV等几种肝炎相关病毒的基因检测 |
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| 引用本文： | 李方和,杨燕,喻植群,朱凡,汪由坤,张俊,赵西平,杨东亮.武汉地区献血员血清TTV等几种肝炎相关病毒的基因检测[J].咸宁医学院学报,2000,14(2):100-102. |
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| 作者姓名： | 李方和 杨燕 喻植群 朱凡 汪由坤 张俊 赵西平 杨东亮 |
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| 作者单位： | 同济医科大学附属同济医院临床免疫研究室,武汉,430030
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| 摘 要： | 了解武汉地区不同献血员血清ＴＴＶ感染特点及其与其它几种肝炎相关病毒感染之间的关系。方法采用ＰＣＲ及巢式ＰＣＲ对５４例武汉市城区义务献血员及７４例既往乡村献血者分别进行血清ＴＴＶ ＤＮＡ，ＨＣＶ ＲＮＡ及ＨＧＶ ＲＮＡ等检测。结果：ＴＴＶ ＤＮＡ、ＨＣＶ ＲＮＡ及ＨＧＶ ＲＮＡ指标阳性率在既 往乡村个体献血员为４３．２％、２３．０％与２．７％，城区义务献血员为５．６％、１．９％与１．９％，前者ＴＴＶ
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| 关 键 词： | 献血员 肝炎 TTV－DNA 基因诊断 |
Detection of TTV DNA and Other Hepatitis Virus in Sera of Blood Donors in WUHAN Area |
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| LI Fanghe,YANG Yan,YU Zhiqun et al Clinic Immunology Research Unit,Tongji Hospital,Tongji Medical Uniwersity,Wuhan.Detection of TTV DNA and Other Hepatitis Virus in Sera of Blood Donors in WUHAN Area[J].Journal of Xianning Medical College,2000,14(2):100-102. |
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| Authors: | LI Fanghe YANG Yan YU Zhiqun Clinic Immunology Research Unit Tongji Hospital Tongji Medical Uniwersity Wuhan |
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| Institution: | LI Fanghe,YANG Yan,YU Zhiqun et al Clinic Immunology Research Unit,Tongji Hospital,Tongji Medical Uniwersity,Wuhan 430030 |
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| Abstract: | Objective To investigate the infective characteristics of TTV and the relationship between it and otter hepatitis associate viruses infection in sera of blood donors in Wuhan area.Methods PCR or RT nested PCR were adopted to detection TTV DNA,HCV RNA and HGV RNA in sera of 54 volunteers and 74 professional blood donors.Results The detection rate of TTV DNA,HCV RNA and HGV RNA were 43.2%,23.0% and 2.7% in professional group and 5.6%,1.9% and 1.9% in voluntteer;the positive rate of TTV DNA and HCV RNA in the former group were obviously higher than in latter(P<0.01).And in two groups,the detectioc rate of TTV DNA was significantly higher than the other hepatitis viruses.Conclusion In professional blood donors there is a high risk for TTV tansmission. |
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| Keywords: | Blood transfusion Hepatitis TTV DNA |
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