| Abstract: | Abstract: In this study, the stomal portion of the gastric remnant mucosa following a gastrectomy for gastric cancer was examined endoscopically and histopathologically. The ODC activity was assayed from biopsies from the stomal portion of the gastric remnant and from the greater curvature. The results obtained can be summarized as follows: 1. Endoscopic changes in the stomal mucosa (redness) were found significantly more often in patients following a B-II than in patients who had had a B-I. Histopathological changes consisting of glandular dilatation and an irregular glandular structure were detected in many of the stomal mucosal specimens. 2. The ODC activity was significantly higher in the stomal portion of the remnant stomach tlian in the greater curvature. As for the stomal portion, ODC activity was significantly higher following a B-II titan following a B-I. In summary, the present findings suggest that active cell proliferation occurs in the gastric remnant mucosa, particularly in the region of anastomosis, and that an enhancement of cell proliferation kinetics plays a role in the pathogenesis of primary cancer in the stomal portion of the remnant stomach. |
