应变-血压指数评价终末期肾病患者中型动脉弹性

目的探讨应用应变-血压指数评价终末期肾病患者肱动脉和胫前动脉弹性的可行性及临床价值。方法随机选取终末期肾病患者39例作为终末期肾病组,健康志愿者46例作为对照组。全部应用应变和应变率成像对肱动脉和胫前动脉进行检查。通过应变和应变率成像获得肱动脉和胫前动脉的最大圆周应变,同时测量被检者肱动脉和胫前动脉血压,计算肱动脉和胫前动脉的应变-血压指数,对终末期肾病组和对照组的参数进行对比分析。结果终末期肾病组的胫前动脉应变-血压指数(4.01%±0.59%)明显低于对照组(5.71%±0.55%,P<0.01);终末期肾病组和对照组的肱动脉应变-血压指数(3.82%±0.39%比3.95%±0.46%)差异无统计学意义(P>0.05)。结论应变-血压指数可以作为评价终末期肾病患者中型动脉弹性改变的新指标。

Elasticity of Medium-Sized Artery in Patients with End-Stage Renal Disease Through Strain-Blood Pressure Index

Aim To investigate the feasibility and the clinical value of strain-blood pressure index(SBPI) in assessing the elasticity of brachial artery and anterior tibial artery in patients with end-stage renal disease(ESRD). Methods 39 patients with ESRD and 46 healthy volunteers were involved.39 patients with ESRD belonged to the case group,and 46 healthy volunteers belonged to the control group.Maximum of circumferential strain(CSmax) of brachial artery and anterior tibial artery were acquired through strain and strain rate imaging(Xstrain).Local blood pressure which included local systolic blood pressure(LSBP) and local diastolic blood pressure(LDBP) of brachial artery and anterior tibial artery were measured at the same time.SBPI were calculated.Parameters were compared between the case group and the control group. Results SBPI of anterior tibial artery in case group(4.01%±0.59%) was less than that in control group(5.71%±0.55%,P<0.01).While SBPI of brachial artery in case group and control group were 3.82%±0.39% and 3.95%±0.46% respectively.There was no significant difference between case group and control group(P>0.05). Conclusion SBPI might be a new index that could evaluate the elasticity of medium-sized arteries in patients with ESRD.