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锰对比剂磁共振成像研究进展
引用本文:龚明福,杨华,邹利光.锰对比剂磁共振成像研究进展[J].中国医学影像技术,2013,29(1):142-145.
作者姓名:龚明福  杨华  邹利光
作者单位:第三军医大学新桥医院放射科,重庆,400037
基金项目:国家自然科学基金(81071197)。
摘    要:基于锰离子的对比剂在肝脏和神经系统MR中的应用具有独特优势。杂合入锰的纳米颗粒具有较常规纳米颗粒更强的顺磁性。目前基于超敏感的锰纳米颗粒的分子影像越来越受到重视。本文针对含锰对比剂在肝脏、神经系统中的应用以及锰纳米颗粒在MR分子影像学中的应用现状进行综述。

关 键 词:锰离子  对比剂  铁酸锰纳米颗粒  磁共振成像
收稿时间:2012/5/25 0:00:00
修稿时间:2012/12/11 0:00:00

Progress in research of magnetic resonance imaging of manganese contrast agent
GONG Ming-fu,YANG Hua and ZOU Li-guang.Progress in research of magnetic resonance imaging of manganese contrast agent[J].Chinese Journal of Medical Imaging Technology,2013,29(1):142-145.
Authors:GONG Ming-fu  YANG Hua and ZOU Li-guang
Institution:Department of Radiology, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China;Department of Radiology, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China;Department of Radiology, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China
Abstract:Manganese ion (Mn2+) is calcium (Ca2+) analog and is also a paramagnetic material. Manganese ion-based MRI contrast agent possesses unique advantage when it is performed in liver and nervous system. The nanoparticles alloyed with manganese have stronger paramagnetic than conventional ones, and molecular imaging based on ultra-sensitive manganese-doped nanoparticles is arousing more and more attention. Application status of manganese contrast agent in liver, nervous system and MR molecular imaging based on nanoparticles alloyed with manganese were reviewed in this article.
Keywords:Manganese ion  Contrast media  Manganese ferrate nanoparticles  Magnetic resonance imaging
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