Incidence of multiple sclerosis in Hordaland, western Norway: a fluctuating pattern |
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Authors: | M Gr?nning T Riise G Kv?le H Nyland J P Larsen J A Aarli |
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Affiliation: | Department of Neurology, Haukeland University Hospital, Bergen, Norway. |
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Abstract: | The incidence of multiple sclerosis (MS) was studied in the county of Hordaland, western Norway. A significant increase in incidence in the period 1958-1987, a decline followed by a gradual increase in mean age at onset, geographic differences in time trends and a biphasic pattern revealed by a birth cohort analysis support the theory of real time-space fluctuations in the incidence of MS over time. |
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