诱发电位检测在失代偿期肝硬化患者亚临床肝性脑病诊断中的价值

目的探讨诱发电位(EP)对亚临床肝性脑病的诊断价值.方法对30例失代偿期肝硬化患者进行脑干诱发电位(BAEP),体感诱发电位(SEP),视觉诱发电位(VEP)检测,并与正常对照组及代偿期肝硬化患者进行比较.结果失代偿期肝硬化患者BAEP异常16例(53.3%),VEP异常15例(50.0%),SEP异常18例(60.0%),总异常率为700%.与正常对照组及代偿期肝硬化患者相比,差异有统计学意义(P＜0.05).结论EP是亚临床肝性脑病的一项客观而敏感的诊断指标,多项EP检测可提高检出率.

Diagnosis of subclinical hepatic encephalopathy with evoked potentials in patients with decompensated hepatic cirrhosis

Objective To evaluate the diagnostic value of evoked potentials (EP) in subclinical hepatic encephalopathy due to liver cirrhosis. Methods Thirty patients with decompensated liver cirrhosis were recruited in the study,and normal subjects and patients with compensated hepatic cirrhosis were served as controls. Brainstem auditory evoked potential (BAEP),visual evoked potential (VEP) and somatosensory evoked potential(SEP) were performed with a neuro-evoked potential monitor. Results The abnormal rates of BAEP,VEP and SEP in decompensated cirrhosis patients were 53.3%,50.0% and 60.0% respectively,with a total abnormal rate of 70.0%. There was a significant difference as compared with those in the normal subjects and the patients with compensated hepatic cirrhosis (P<0.05). Conclusions EP measurement might be a sensible and objective method for the evaluation of subclinical hepatic encephalopathy due to liver cirrhosis,particularly three evoked potentials are performed simultaneously.