Retrospective evaluation of the efficacy of the BCG vaccination campaign of newborns in Barcelona,Spain |
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| Institution: | 4. Chest Clinic, Tuberculosis Prevention and Control Centre, Barcelona Spain;1. Department of Biostatistics, University of Barcelona, Barcelona, Spain;2. Department of Preventative Medicine and Public Health, University of Barcelona, Barcelona, Spain;3. General Directorate of Public Health, Department of Health and Social Security, Barcelona, Spain;1. Department of Clinical Sciences, Institute of Tropical Medicine, Nationalestraat 155, Antwerp 2000, Belgium;2. Department of Internal Medicine, University of Gondar, Post Office Box 196, Gondar, Ethiopia;1. Disease Biophysics Group, Wyss Institute for Biologically Inspired Engineering, John A. Paulson School of Engineering and Applied Sciences, Harvard University, 29 Oxford Street, Pierce Hall 318, Cambridge, MA 02138, USA;2. US Army Combat Capabilities Development Command Soldier Center, Natick, MA 01760, USA;3. Department of Chemistry and Life Science, United States Military Academy, West Point, NY 10996, USA;1. School of Life Sciences, Chinese University of Hong Kong, Hong Kong, China;3. Hong Kong Bioinformatics Centre, Chinese University of Hong Kong, Hong Kong, China;5. School of Biomedical Sciences, Chinese University of Hong Kong, Hong Kong, China;2. State Key Laboratory of Respiratory Disease for Allergy at Shenzhen University, Shenzhen, China;4. Shenzhen Key Laboratory of Allergy and Immunology, School of Medicine, Shenzhen University, Shenzhen, China;6. State Key Laboratory of Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China;1. Research Center for Structural Materials, National Institute for Materials Science, 1-2-1 Sengen, Tsukuba, Ibaraki, 305-0047, Japan;2. Department of Mechanical Engineering and Science, Doshisha University, 1-3 Miyakodani, Tatara, Kyotanabe, 610-0394, Japan;3. Department of Materials Science, Graduate School of Engineering, Tohoku University, 6-6-11 Aoba, Aramaki, Aoba-ku, Miyagi, 980-8579, Japan;4. Department of Mechanical Engineering, Toyohashi University of Technology, 1-1 Hibarigaoka, Tempaku, Toyohashi, Aichi, 441-8580, Japan;1. Child and Adolescent Mental Health Team, Selkirk, NHS Borders, UK;2. Clinical and Health Psychology, School of Health in Social Science, University of Edinburgh, UK |
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| Abstract: | The efficacy of the BCG vaccination campaign of neonates in Barcelona, carried out in the period 1966–1974, was evaluated with a study of cases and controls made during the period 1978–1988 in patients between the ages of 4 and 21 years. It shows that the efficacy of this vaccination campaign was 32%, that it was greater in men than women and that it decreased with the passage of time. The number of cases of tuberculosis prevented by this campaign is calculated at 13.4%.Given that the vaccine used offered maximum guarantees, the authors consider that this poor efficacy must be attributed to operational deficiencies in the vaccination campaign itself. |
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