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Symptoms of pulmonary tuberculosis in consecutive smear-positive cases treated in Ethiopia
Affiliation:1. Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea;2. Department of Clinical Pharmacology & Therapeutics, Samsung Medical Center, Seoul, Republic of Korea;3. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Republic of Korea;1. Cardiovascular Risk and Nutrition Research Group (CARIN), Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain;2. Biomedicine Program, Department of Experimental and Health Sciences, Pompeu Fabra University, Barcelona, Spain;3. CIBER de Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain;4. Department of Nursing, School of Health Sciences. University of Málaga, Málaga, Spain;5. Cardiovascular Epidemiology and Genetics Research Group, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain;6. CIBER Epidemiologia y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain;7. Department of Preventive Medicine and Public Health, University of Navarra-Navarra Institute for Health Research, Pamplona, Spain;8. Primary Health Care Services-Osasunbidea, Pamplona, Navarra, Spain;9. Human Nutrition Unit, University Hospital of Sant Joan de Reus Department of Biochemistry and Biotechnology, Pere Virgili Institute for Health Research, Rovira i Virgili University, Reus, Spain;10. Department of Preventive Medicine, University of Valencia, Valencia, Spain;11. Research Institute of Biomedical and Health Sciences, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain;12. Instituto de Investigación Sanitaria Illes Balears (IdISBa), University Hospital of Son Espases, Palma de Mallorca, Spain;13. Department of Internal Medicine, Hospital Clínic, IDIBAPS August Pi i Sunyer Biomedical Research Institute, University of Barcelona, Barcelona, Spain;14. Department of Nutrition, Food Sciences and Physiology, Center for Nutrition Research, University of Navarra, Pamplona, Spain, Madrid Institute for Advanced Studies (IMDEA) Food Institute, Madrid, Spain;15. Lipid Unit, Department of Internal Medicine, Bellvitge Biomedical Research Institute (IDIBELL)-Hospital Universitari de Bellvitge, L''Hospitalet de Llobregat, Barcelona, Spain;p. Department of Endocrinology and Nutrition, University Hospital Fundación Jiménez Díaz, Madrid, Spain;q. Department of Endocrinology and Nutrition, Hospital Clínic, Barcelona, Spain;r. CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III, Madrid, Spain;s. Research Group on Community Nutrition and Oxidative Stress, University of the Balearic Islands, Palma de Mallorca, Spain;t. OSI ARABA. University Hospital Araba, Department of Cardiology University of the Basque Country UPV/EHU Vitoria-Gasteiz, Spain;u. Department of Biochemistry and Biotechnology, Human Nutrition Unit, Hospital Universitari Sant Joan de Reus, Reus, Spain;1. College Veterinary Medicine, Haramaya University, P.O. Box 138, Dire Dawa, Ethiopia;2. School of Veterinary Medicine, Hawassa University, P.O. Box 05, Hawassa, Ethiopia;3. Department of Animal Science, College of Agriculture and Natural Resource Sciences, Debre Berhan University, P.O. Box 445, Debre Berhan, Ethiopia;4. National Veterinary Institute, P.O. Box 19, Bishoftu, Ethiopia;5. College of Veterinary Medicine and Agriculture, Addis Ababa University, P.O. Box 34, Bishoftu, Ethiopia;6. Aklilu Lemma Institute of Pathobiology, Addis Ababa University, P.O. Box 1176, Addis Ababa, Ethiopia;1. Department of Training and Exercise Science, Faculty of Sport Science, Ruhr-University Bochum, Germany;2. Unit of Sport Psychology, Faculty of Sport Science, Ruhr-University Bochum, Germany;3. School of Human Movement and Nutrition Sciences, The University of Queensland, Brisbane, Australia;4. Institute of Sports and Preventive Medicine, Saarland University, Saarbrücken, Germany;5. Institute of Sports Science, Johannes-Gutenberg University, Mainz, Germany;1. Military Performance Division, U.S. Army Research Institute of Environmental Medicine, USA;2. Human Resources Research Organization, USA;1. Armauer Hansen Research Institute, PO Box 1005, Addis Ababa, Ethiopia;2. Swiss Tropical and Public Health Institute, Socinsstr. 57, 4002 Basel, Switzerland;3. Centre for Molecular Bacteriology and Infection, MRC National Institute for Medical Research, Mill Hill, London NW7 1AA, United Kingdom
Abstract:The purpose of the study was to define in detail the usually accepted respiratory and non-respiratory symptoms of newly discovered smear-positive pulmonary tuberculosis in a group of Ethiopians. There were 163 consecutive patients referred to the weekly Chest Clinic at the Tuberculosis Demonstration and Training Centre in Addis Ababa.The results showed that more than 5% of pulmonary tuberculosis cases had respiratory symptoms of less than 2 weeks. Some symptoms such as haemoptysis, chest pain and dyspnoea prompted early reporting while there was a delay in reporting other symptoms such as cough, in spite of cough being present in all patients. Most of the non-respiratory (constitutional) symptoms were reported fairly early.A history of tuberculosis contact was relevant in this group of patients. A negative Mantoux test was noted in 20% of patients.
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