Diabetes and atherosclerosis |
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| Affiliation: | 1. Research and Development, Molekule Inc, 3802 Spectrum Blvd., Tampa, FL 33612, USA;2. Clean Energy Research Center, Department of Chemical, Biological and Materials Engineering, University of South Florida, 3820 Spectrum Blvd, Tampa, FL 33612, USA;3. Department of Chemistry, Sri Guru Teg Bahadur Khalsa College, Anandpur Sahib, Punjab 140118, India;4. CICECO – Aveiro Institute of Materials, Department of Chemistry, University of Aveiro, Aveiro 3810-193, Portugal;1. Department of Organic and Pharmaceutical Chemistry, School of Pharmacy, University of Navarra, Irunlarrea 1, 31010 Pamplona, Spain;2. Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland;3. Department of Medical Microbiology and Immunobiology, Faculty of Medicine, University of Szeged, Dóm tér 10, 6720 Szeged, Hungary;4. Division of Bioorganic Chemistry, Saarland State University, Campus, Geb. B2.1, 66123, Saarbruecken, Germany;1. Latvian Institute of Organic Synthesis, Aizkraukles 21, 1006 Riga, Latvia;2. Latvian Biomedical Research and Study Centre, Ratsupites 1, 1067 Riga, Latvia;1. Departamento de Parasitología, Instituto de Investigación Biosanitaria (ibs.GRANADA), Hospitales Universitarios De Granada/Universidad de Granada, Granada, Spain;2. Department of Chemistry, Universitat de les Illes Balears, E- 07122 Palma de Mallorca, Spain;3. Departamento de Estadística, Facultad de Ciencias, Universidad de Granada, E-18071 Granada, Spain;1. Department of Orthopedics, The Second Affiliated Hospital of Xi''an Jiaotong University, Xian 710004, PR China;2. Department of Spinal Surgery, The Second Affiliated Hospital of Henan University of Science and Technology, Luoyang 471000, PR China;3. Medical College, Henan University of Science and Technology, Luoyang 471003, PR China;4. Department of Breast Surgery, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, Luoyang, PR China |
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| Abstract: | Atherosclerosis is the most important complication of diabetes and diabetes is an important risk factor for cardiovascular disease. Atherosclerosis develops more rapidly and at an earlier age in diabetic patients than in non-diabetic people. Although a number of cardiovascular risk factors are more common in diabetic than non diabetic people, these do not entirely account for the increased frequency of cardiovascular disease. The identity of the additional factor or factors which result in increased atherosclerosis in diabetes is unknown but attention should be paid to the role of glycated lipoproteins and of hyperinsulinaemia. In treating diabetic patients, attention should be paid to cardiovascular risk factors such as dyslipidaemia and hypertension as well as to the control of blood glucose. |
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