| 替硝唑凝胶处方筛选研究 |
| |
| 引用本文： | 申国庆,魏峻,单萍萍. 替硝唑凝胶处方筛选研究[J]. 药学与临床研究, 2001, 9(1): 1-2 |
| |
| 作者姓名： | 申国庆 魏峻 单萍萍 |
| |
| 作者单位： | 中国协和医科大学、中国医学科学院皮肤病研究所,南京,210042 |
| |
| 摘 要： | 为筛选具有抗氧、防腐及耐寒的替硝唑凝胶处方,本文采用正交法、选择溶媒、抗氧剂和防腐剂三个可变因素,并设置不同水平进行实验比较.结果表明,以丙二醇和乙醇作替硝唑的混合溶媒,并配以抗氧剂获得质量稳定的替硝唑凝胶.
|
| 关 键 词： | 正交法 替硝唑 稳定性 |
| 修稿时间： | 2000-03-20 |
Selection of Stable Formula of Tinidazole Gel by Orthogonal Design |
| |
| Shen Guoqing,Wei Jun,Shan PingpingInstitute of Dermatology,Chinese Academy of Medical Sciences,Peking Union Medical University,. Selection of Stable Formula of Tinidazole Gel by Orthogonal Design[J]. Pharmacertical and Clinical Research, 2001, 9(1): 1-2 |
| |
| Authors: | Shen Guoqing Wei Jun Shan PingpingInstitute of Dermatology Chinese Academy of Medical Sciences Peking Union Medical University |
| |
| Affiliation: | Nanjing 210042 |
| |
| Abstract: | For selecting the formula of tinidazole gel on antioxidation, antiseptic effect and cold-resistance, three variable factors and three levels of solvents, antioxider and antiseptic were decided by orthogonal design, and the experimental comparisons were made. The experiment results show that tinidazole gel is stable in the mixed solvents of propanediol and ethanol with antioxider. |
| |
| Keywords: | Orthogonal design Tinidazole Stability |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
