Effects of therapy with [<Superscript>177</Superscript>Lu-DOTA<Superscript>0</Superscript>,Tyr<Superscript>3</Superscript>]octreotate on endocrine function期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Effects of therapy with [177Lu-DOTA0,Tyr3]octreotate on endocrine function

Authors:	Jaap J. M. Teunissen Eric P. Krenning Frank H. de Jong Yolanda B. de Rijke Richard A. Feelders Maarten O. van Aken Wouter W. de Herder Dik J. Kwekkeboom

Affiliation:	(1) Department of Nuclear Medicine, Erasmus Medical Center, ‘s-Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands;(2) Department of Internal Medicine, Erasmus Medical Center, ‘s-Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands;(3) Department of Clinical Chemistry, Erasmus Medical Center, ‘s-Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands

Abstract:	Purpose Peptide receptor radionuclide therapy (PRRT) with radiolabelled somatostatin analogues is a novel therapy for patients with somatostatin receptor-positive tumours. We determined the effects of PRRT with [¹⁷⁷Lu-DOTA⁰,Tyr³]octreotate (¹⁷⁷Lu-octreotate) on glucose homeostasis and the pituitary-gonadal, pituitary-thyroid and pituitary-adrenal axes.

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