上海宝山地区亚临床甲状腺功能减退症的流行病学研究

目的分析上海宝山地区亚临床甲状腺功能减退的流行病学特点。方法 2004年5月至2005年2 月对上海宝山地区2 780人进行血清甲状腺激素浓度和血脂测定。结果 2780例中,血清促甲状腺激素(TSH)浓度>5 mU/L为179例,其中临床甲状腺功能减退9例,亚临床甲状腺功能减退170例。亚临床甲状腺功能减退发病率为6．1％,其中男性为2．3％,女性为7．8％。亚临床甲状腺功能减退患病率随年龄增加而升高。血清 TSH浓度与总胆固醇水平呈正相关(r=0．141,P=0．003)。本区人群的尿碘水平属于正常范围。结论上海宝山地区的亚临床甲状腺功能减退患病率较高,且与年龄和性别相关。

Prevalence of subclinical hypothyroidism in Shanghai suburb Baoshan area

Objective To analyze the epidemiological features of subclinical hypothyroidism in the Shanghai suburb Baoshan region. Methods Between May 2004 and February 2005' serum levels of TSH, FT3 and FT4 and lipid profile in 2 780 subjects were detected in the Shanghai suburb Baoshan area. Results The overall prevalence of subclinical hypothyroidism was 6.1%, which was correlated positively with age. The prevalence was significantly higher in females (7. 8%) than in males (2. 3%). Serum thyrotropin was closely in positive corelation to plasma cholesterol levels (r = 0. 141, P = 0. 003). Conclusion The prevalence of subclinical hypothyroidism is high in the Shanghai suburb Baoshan area, probably corelative with age and sex but with normal mine iodine level.