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Sustained release and enhanced oral bioavailability of rivaroxaban by PLGA nanoparticles with no food effect
Authors:Anwer  Md. Khalid  Mohammad   Muqtader  Iqbal   Muzaffar  Ansari   Mohd Nazam  Ezzeldin   Essam  Fatima   Farhat  Alshahrani   Saad M.  Aldawsari  Mohammed F.  Alalaiwe  Ahmed  Alzahrani  Aiman A.  Aldayel  Abdullah M.
Affiliation:1.Department of Pharmaceutics, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, 11942, Saudi Arabia
;2.Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia
;3.Bioavailability Laboratory, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia
;4.Department of Pharmacology, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, 11942, Saudi Arabia
;
Abstract:Journal of Thrombosis and Thrombolysis - The purpose of the currents study was to enhance bioavailability of rivaroxaban (RXB) and reduce the food effect. RXB loaded PLGA nanoparticles...
Keywords:
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