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宁泌泰胶囊联合左氧氟沙星治疗细菌性前列腺炎的临床疗效
引用本文:周睿,朱劲松,陈志洁,鲍彤. 宁泌泰胶囊联合左氧氟沙星治疗细菌性前列腺炎的临床疗效[J]. 药物评价研究, 2021, 0(2): 403-406
作者姓名:周睿  朱劲松  陈志洁  鲍彤
作者单位:安徽医科大学附属安庆医院(安庆市立医院)
摘    要:目的 宁泌泰胶囊联合左氧氟沙星治疗细菌性前列腺炎的临床疗效.方法 选取2018年1月-2019年9月安徽医科大学安庆附属医院收治的62例细菌感染性前列腺炎患者作为研究对象,根据治疗方案的不同将患者分为对照组和观察组,每组31例.对照组患者静脉滴注盐酸左氧氟沙星注射液,0.4g/d;观察组在对照组基础上口服宁泌泰胶囊,3...

关 键 词:宁泌泰胶囊  左氧氟沙星  细菌性前列腺炎  白细胞数量  美国国立卫生研究院前列腺炎症状指数评分  不良反应

Clinical efficacy of Ningmitai Capsules combined with levofloxacin in treatment of bacterial prostatitis
ZHOU Rui,ZHU Jinsong,CHEN Zhijie,BAO Tong. Clinical efficacy of Ningmitai Capsules combined with levofloxacin in treatment of bacterial prostatitis[J]. Drug Evaluation Research, 2021, 0(2): 403-406
Authors:ZHOU Rui  ZHU Jinsong  CHEN Zhijie  BAO Tong
Affiliation:(Anqing Affiliated Hospital of Anhui Medical University(Anqing Municipal Hospital),Anqing 246003,China)
Abstract:Objective To investigate the clinical efficacy of Ningmitai Capsules combined with levofloxacin in treatment of bacterial infectious prostatitis.Methods A total of 62 patients with bacterial prostatitis admitted to Anqing Affiliated Hospital of Anhui Medical University from January 2018 to September 2019 were selected as the study subjects.According to different treatment regiments,the patients were divided into control group and observation group,with 31 patients in each group.Patients in the control group were intravenously injected with Levofloxacin Hydrochloride Injection,0.4 g/d.Patients in the observation group were po administered with Ningmitai Capsules on the basis of control group,3 tablets/time,three times daily.Patients in two groups were treated for two weeks.The clinical efficacy in two groups was observed,and the count of white blood cells in urine and prostatic fluidwhite,and NIH-CPSI score before and after treatment in two groups were compared.Results After treatment,the total effective rate of the control group was 93.54%,which was significantly higher than 77.42%of control group,with statistically significant difference(P<0.05).After treatment,the number of white blood cells in urine and prostatic fluid of two groups was significantly decreased(P<0.01).After treatment,the number of white blood cells in urine and prostatic fluid in the observation group was significantly lower than those in the control group,and the difference was statistically significant(P<0.01).After treatment,NIHCPSI scores were significantly decreased in two groups,and the difference was statistically significant(P<0.05).After treatment,the NIH-CPSI score in the observation group was significantly lower than that in the control group,and the difference was statistically significant(P<0.05).During the treatment,the number of nausea and vomiting,abdominal pain and diarrhea in the observation group was significantly lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Ningmitai Capsules combined with levofloxacin in treatment of bacterial prostatitis has a good clinical effect,the incidence of adverse reactions is low,worthy of clinical promotion.
Keywords:Ningmitai Capsules  levofloxacin  bacterial prostatitis  count of white blood cells  NIH-CPSI score  adverse reactions
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