| 艰难梭菌毒素及其检测方法研究进展 |
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| 引用本文： | 龙思鸿,谢群,孙珊珊,曹琴,曾汇文,贺莉萍.艰难梭菌毒素及其检测方法研究进展[J].南华大学学报(医学版),2022(6):941-944. |
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| 作者姓名： | 龙思鸿 谢群 孙珊珊 曹琴 曾汇文 贺莉萍 |
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| 作者单位： | 内蒙古医科大学研究生院,内蒙古自治区呼和浩特市 010000;内蒙古包钢医院 内蒙古医科大学第三附属医院 皮肤性病科,内蒙古自治区包头市 014010;内蒙古包钢医院 内蒙古医科大学第三附属医院 皮肤性病科,内蒙古自治区包头市 014010;北京大学第三医院皮肤科,北京市 100191 |
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| 基金项目： | 内蒙古自治区自然科学基金面上项目(2019MS08041) 作者简介:张婷,硕士研究生,研究方向为色素性皮肤病,E-mail为17839224257@163.com。通信作者郝玉琴,主任医师,教授,硕士研究生导师,研究方向为色素性皮肤病及皮肤免疫等,E-mail为haoyuqin0472@163.com。 |
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| 摘 要： | ]黄褐斑是一种多因素作用诱发的慢性色素性皮肤病。黑色素合成活跃及皮损处炎症反应是其主要特点,因此黑色素合成、炎症、氧化应激成为黄褐斑治疗的期望靶点。本文从抑制黑色素合成、抗炎及抗氧化应激方面进行综述。
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| 关 键 词： | 黄褐斑 黑色素 炎症反应 靶点 信号通路 [ |
| 收稿时间： | 2021/11/16 0:00:00 |
| 修稿时间： | 2022/9/5 0:00:00 |
Research progress of Clostridium difficile toxin and its detection methods |
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| LONG Sihong,XIE Qun,SUN Shanshan,CAO Qin,ZENG Huiwen,HE Liping.Research progress of Clostridium difficile toxin and its detection methods[J].Journal of Nanhua University(Medical Edition),2022(6):941-944. |
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| Authors: | LONG Sihong XIE Qun SUN Shanshan CAO Qin ZENG Huiwen HE Liping |
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| Institution: | Graduate School, Inner Mongolia Medical University, Hohhot 010000, Inner Mongolia, China;Department of Dermatology, Inner Mongolia Baogang Hospital, the Third Affiliated Hospital of Inner Mongolia Medical University, Baotou 014010, Inner Mongolia, China; Department of Dermatology, Inner Mongolia Baogang Hospital, the Third Affiliated Hospital of Inner Mongolia Medical University, Baotou 014010, Inner Mongolia, China;Department of Dermatology, Peking University Third Hospital, Beijing 100191, China |
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| Abstract: | Melasma is a chronic pigmented skin disease induced by multiple factors. Active melanin synthesis and inflammatory response at the lesions are its main features; therefore, melanin synthesis, inflammation, and oxidative stress have become the desired targets for melasma treatment. In this paper, we review in terms of inhibition of melanin synthesis, anti-inflammatory and anti-oxidative stress aspects. |
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| Keywords: | melasma melanin inflammation target signaling pathways |
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