| 松郁安神方对不同中医证型失眠患者血浆中5-羟色胺及多巴胺水平的影响 |
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| 引用本文： | 黄俊山,曾雪爱,黄兆迁,吴文宝,王雅丽,樊书领,陈铭奇. 松郁安神方对不同中医证型失眠患者血浆中5-羟色胺及多巴胺水平的影响[J]. 中医杂志, 2011, 52(24): 2119-2120,2124 |
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| 作者姓名： | 黄俊山 曾雪爱 黄兆迁 吴文宝 王雅丽 樊书领 陈铭奇 |
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| 作者单位： | 福建省中医药研究院,福建省福州市五四路282号,350003 |
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| 基金项目： | 福建省公益类科研院所基本科研专项项目(2009R10007-1); 福建省中医药科研项目重点课题(wzzs0901) |
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| 摘 要： | 目的 观察松郁安神方对肝郁化火及阴虚火旺证单纯性失眠患者血浆中5-羟色胺(5-HT)、多巴胺(DA)的影响,探讨其治疗失眠的可能作用机制. 方法 60例单纯性失眠患者中肝郁化火和阴虚火旺患者各30例,均予松郁安神方治疗8周.两组患者治疗前后进行阿森斯失眠量表(Athens)评定及测定血浆5-HT和DA含量. 结果 两组患者治疗后Athens评分与本组治疗前比较,均有统计学差异(P＜0.05).两组患者治疗后5-HT水平较治疗前明显升高(P＜0.05或P＜0.01),DA水平较治疗前明显降低(P＜0.05).结论 松郁安神方对肝郁化火证和阴虚火旺证失眠患者疗效确切,可能是升高5-HT含量及降低DA含量而起到改善睡眠的作用.
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| 关 键 词： | 失眠 松郁安神方 5-羟色胺 多巴胺 |
Influence of Songyu Anshen Formula on the Level of 5-hydroxy Tryptamine and Dopamine in Insomnia Patients with Different TCM Syndromes |
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| HUANG Junshan , ZENG Aixue , HUANG Zhaoqian , WU Wenbao , WANG Yali , FAN Shuling , CHEN Mingqi. Influence of Songyu Anshen Formula on the Level of 5-hydroxy Tryptamine and Dopamine in Insomnia Patients with Different TCM Syndromes[J]. Journal of Traditional Chinese Medicine, 2011, 52(24): 2119-2120,2124 |
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| Authors: | HUANG Junshan ZENG Aixue HUANG Zhaoqian WU Wenbao WANG Yali FAN Shuling CHEN Mingqi |
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| Affiliation: | HUANG Junshan,ZENG Aixue,HUANG Zhaoqian,WU Wenbao,WANG Yali,FAN Shuling,CHEN Mingqi(Fujian Academy of Traditional Chinese Medicine,Fuzhou 350003) |
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| Abstract: | Objective To study the effect and possible mechanism of Songyu Anshen Formula [Formula of Gansong(Rhizoma Nardostachyos) and Yujin(Radix Curcumae) for calming the mind] on insomnia by observing its influence on 5-hydroxy tryptamine(5-HT) and dopamine(DA) of simple insomnia patients with the syndrome of stagnated liver qi transformed into fire and syndrome of yin deficiency with fire in TCM.Methods Sixty simple insomnia patients,30l with the syndrome of stagnated liver qi transformed into fire and 30 with th... |
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| Keywords: | Insomnia Songyu Anshen Formula [Formula of Gansong(Rhizoma Nardostachyos) and Yujin(Radix Curcumae) for calmng the mind] 5-hydroxy tryptamine(5-HT) dopamine(DA) |
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