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通阳解毒汤治疗结节囊肿型痤疮44例临床观察
引用本文:丁旭,刘瓦利. 通阳解毒汤治疗结节囊肿型痤疮44例临床观察[J]. 中医杂志, 2011, 52(24): 2121-2124
作者姓名:丁旭  刘瓦利
作者单位:中国中医科学院广安门医院皮肤科,北京市西城区广安门内大街北线阁5号,100053
摘    要:目的 评价通阳解毒汤治疗结节囊肿型痤疮的临床疗效.方法 选择结节囊肿型痤疮中医辨证为阳郁寒凝证型患者87例,随机分为治疗组44例和对照组43例,治疗组口服通阳解毒汤,每日1剂,分早、晚2次温服.对照组口服大黄廑虫丸,每次3g,每日2次.两组疗程均为8周.比较两组患者临床疗效,观察两组患者治疗前及治疗后2、4、6、8周时皮损评分、中医证候评分的变化及不良反应.结果 治疗组总有效率86.4%,对照组总有效率65.1%,治疗组疗效优于对照组(P<0.05).两组患者总积分从治疗后2周起均有明显下降,治疗后8周分别与本组治疗前、治疗后2周、4周、6周比较差异有统计学意义(P<0.01).从治疗后4周起治疗组总积分与对照组同时间比较,差异均有统计学意义(P<0.05或P<0.01).从治疗后2周起比较总积分下降率、中医证候评分下降率,治疗组均优于对照组(P<0.01);在皮损评分下降率、不良反应发生率方面,两组比较差异无统计学意义(P>0.05).结论 通阳解毒汤治疗阳郁寒凝型结节囊肿型痤疮疗效较好.

关 键 词:结节囊肿型  痤疮  阳郁寒凝证  温通  通阳解毒汤

Clinical Observation on Tongyang Jiedu Decoction in Treating Nodular-cystic Acne:A Report of 44 Cases
DING Xu , LIU Wali. Clinical Observation on Tongyang Jiedu Decoction in Treating Nodular-cystic Acne:A Report of 44 Cases[J]. Journal of Traditional Chinese Medicine, 2011, 52(24): 2121-2124
Authors:DING Xu    LIU Wali
Affiliation:DING Xu,LIU Wali(Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053)
Abstract:Objective To evaluate the therapeutic effect of Tongyang Jiedu Decoction(Decoction for circulating yang and toxic substances) in treating nodular-cystic acne.Methods The 87 patients with nodular-cystic acne in TCM syndrome of yang stagnation and cold obstruction were randomized into 2 groups.The 44 in the treatment group were treated with Tongyang Jiedu Decoction for oral taking,one dose per day,taken in the morning and in the evening respectively,and the 43 in the control group were treated with Dahuang Zh...
Keywords:nodular-cystic acne  syndrome of yang stagnation and cold obstruction  warming to remove obstruction  Tongyang Jiedu Decoction(Decoction for circulating yang and toxic substances)  
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