HLA in Egyptian children with biliary atresia |
| |
| Authors: | A-Kader Hassan H El-Ayyouti Moustafa Hawas Samia Abdalla Ahmed Al-Tonbary Yousif Bassiouny Mohammed Boneberg Anna El-Sallab Shadia |
| |
| Affiliation: | Department of Pediatrics, Upstate Medical University, Syracuse, New York 13210, USA. |
| |
| Abstract: | We studied the human leukocytes antigens in 18 Egyptian children with biliary atresia (BA) without extrahepatic congenital malformations. There was a significant increased frequency of both B8 and DR3 (83.3% and 94.4% in patients with BA compared with 6.5% and 14.9% in the general population, respectively). Ten patients had the B8/DR3 haplotype. Our results support the hypothesis that genetic factors may play a role in susceptibility to BA. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ |
