冠心病心肌缺血非心脏手术术间术后的临床干预

目的:观察复方丹参注射液用于冠心病非心脏手术术中心肌缺血的治疗。方法:冠心病非心脏手术113例,随机分为对照组57例(术中缺血时仅用硝酸酯类等药物对症治疗),观察组56例(术中同时加入复方丹参注射液治疗)。术中及术毕观察心电图(ECG)、心率(HR)、平均动脉压(MAP)、脉搏血氧饱和度(SPO2)、手术失血量及C反应蛋白(CRP)。ECG做为疗效评定标准。结果:观察组总有效率94.64%(53/56),对照组总有效率36.84%(21/57)(P<0.01),观察组HR无明显变化,而对照组HR增快(P<0.05)。MAP、SPO2治疗前后或组间比较无显著差异;失血量两组无明显差异。结论:复方丹参注射液对冠心病非心脏手术术中心肌缺血有明显的改善和保护作用。

Clinical interfering with ischemic coronary heart disease undergoing non-heart surgery during perioperation

Objective:To observe the preventing and treatming effect of salvia mihiorrhiza composita(SMC)on patients with ischemic coronary heart disease(CHD)undergoing ono-heart surgery.Methods:The 113 patients were randomly divided into the comparison group and SMC group.In the SMC group,each patient of 56 were administered SMC intravenously during the operation ECG,HR,MAP and SPO2 were observed and bleeding quantity was measured perioperatively.Results:Effective rate of ECG in SMC group was 94.64%(53/56) and the comparison group was 36.84%(21/57).There was signifieant difference between the two groups(P<0.01).HR of the SMC group was no great flutter but comparison group became faster(P<0.05).MAP and SpO2of the two groups were no significant difference perioperatively.There was no significant difference to bleeding quantity between the two groups.Conclusion:SMC could effectively improve and protect myocardial ischemia in patients with CHD undergoing ono-heart surgery.