肾移植患者术后营养支持对血脂、肾功能和部分营养指标的观察

目的 探讨肾移植患者嗣手术期的营养支持方法.方法 将肾移植术后进行营养支持的67例患者随机分为A组(相对高氮摄入量组,n=24)、B组(中等氮摄入量组,n=25)和C组(相对低氮摄入量组,n=18).检测其术前1 d和术后2周的血红蛋白、白蛋白、部分营养指标、血脂水平以及肾功能的恢复情况.结果 3组间体重差异无显著性;A组氮平衡显著优于B组和C组(P＜0.05);A组和B组血清白蛋白和血红蛋白比较差异无显著性,但是显著高于C组(P＜0.05);C组肾功能指标恢复优于A组和B组(P＜0.05);3组甘油三酯水平差异无显著性,A组胆同醇水平显著高于B组和C组(P＜0.05),B组和C组比较差异无显著性.结论 肾移植术后早期适宜的氮供给量不仅可以减轻移植肾的负担,促进肾脏功能的恢复,还可以改善患者的营养状况.

Effectiveness of early post-operative nutritional support for kidney transplant recipients

Objective To investigate the early post-operative nutritional support for kidney transplant recipients.Methods Totally 67 patients who received early post-operative nutrition supports were randomly divided into three groups:group A (n = 24,relatively high nitrogen intake),group B (n = 25,intermediate nitrogen intake) and group C (n = 18,relatively low nitrogen intake).Two weeks after operation,albumin,hemoglobin,the nutrition indieators,serum lipids,and renal function 1 day before operation and 2 weeks after operation were evaluated. Results Body weight was significantly different among three groups;the nitrogen balance in group A was significantly better than those in groups B and C (P ＜0.05);albumin and hemoglobin were not significantly different between group A and group B (P ＞ 0.05),but were significantly higher than those in group C (P ＜ 0.05).The renal function in group C was significantly better than those in group A and group B (P ＜ 0.05).The triglyceride level was not significantly different among three groups,while the cholesterol level in group A was significantly higher than those in group B and group C (P ＜ 0.05),but not between group B and group C.Conclusion Proper nitrogen intake in early post-operative nutrition support can improve the recovery of renal function and nutritional status in kidney transplant recipients.