兔颈总动脉创伤性假性动脉瘤模型的建立

目的 为创作性假性动脉瘤（ＴＰＡ）血管内栓塞治疗模型。方法 运用显微外科操作，用双极电凝在１２只兔的右侧胸关肌上烧灼出洞穴，并纵行切开洞穴对应处的右侧颈总动脉，褥式缝合二的开口。结果 １２只兔 于术后６￣１２ｄ出现搏动性包块，３只兔因ＴＰＡ破裂出血分别死于术后第９ｄ、１２ｄ、１７ｄ。余９个ＴＰＡ的影像学、血流动力学及病理检查证实其发生机制及病理特征与人类ＴＰＡ相同。结论 此模型可作ＴＰＡ血管内栓

Establishment of Traumatic Pseudoaneurysm Model of Common Canotid Artery in Rabbits

Objective To establish an appropriate animal model for the study of endovascular treatment of traumatic pseud-oanerysm (TPA). Methods A cavity was made by cauterizing the right sterno-cephalicus muscle in each of 12 rabbits with bipolar electric coagulation forceps and the wall of the right common carotid artery opposite to the cavity was incised longitudinally, the two oriffices were anastomosed by mattress suture. All manipulation was performed microsurgically. Results A pulsatile mass occurred in the right common carotid artery of each rabbit. Three rabbits died of rupture of the TPA the 9th, 12th and 17th day after the operation respectively. It was proved that the pathogenetic mechanisms and the morphorlogical, hemodynamic and pathological features in the other 9 TPAs were similar to those in human TPAs. Conclusion The present animal model is an optimal tool for endo- vascular treatment research on the PTA.