Synthetic peptide, a fragment of the β-subunit of chorionic gonadotropin, inhibits mitogen-stimulated proliferation of human lymphocytesin vitro |
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| Authors: | A. N. Valuiskikh Yu. A. Romashkova A. V. Danilkovich K. G. Freze G. T. Sukhikh E. V. Makarov |
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| Affiliation: | (1) Department of Cellular Physiology and Immunology, Biological Faculty, M. V. Lomonosov Moscow State University, Moscow;(2) Laboratory of Clinical Immunology, Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health, Moscow;(3) Laboratory of Peptide Reception, M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow |
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| Abstract: | Similar to chorionic gonadotropin, synthetic fragment of the β-subunit of chorionic gonadotropin (128th–145th amino acid), inhibits mitogen-stimulated proliferation of human lymphocytesin vitro and binds to membrane receptors of human peripheral blood monocytes. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 123, No. 3, pp. 319–322, March, 1997 |
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| Keywords: | chorionic gonadotropin peptide lymphocytes proliferation inhibition |
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