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检测CEA、CYFRA21-1及脱落细胞鉴别诊断102例胸腔积液临床评价
引用本文:惠雅琳,陆育红,赵勇. 检测CEA、CYFRA21-1及脱落细胞鉴别诊断102例胸腔积液临床评价[J]. 延安大学学报(医学科学版), 2011, 9(1): 27-28
作者姓名:惠雅琳  陆育红  赵勇
作者单位:武警工程学院医院急诊科,陕西,西安,710086
摘    要:目的探讨胸腔积液及血清中癌胚抗原(CEA)、细胞角蛋白片段抗原21-1(CYFRA21-1)及胸腔积液脱落细胞在良恶性胸腔积液鉴别诊断中的价值。方法测定51例结核性与51例癌性胸腔积液患者胸水及血清中的CEA、CYFRA21-1的含量,并行胸水脱落细胞检查。结果 CEA和CYFRA21-1对恶性胸腔积液诊断的敏感性及特异性分别为83%,71%和79%,75%。联合检测胸水脱落细胞,其敏感性和特异性均提高到100%。结论多种方法联合检测具有互补作用,能提高诊断准确率。

关 键 词:癌胚抗原  细胞角蛋白片段抗原21-1  脱落细胞  诊断

Clinical evaluation of the differentiating diagnosis of 102 patients with pleural effusion by detection of CEA,CYFRA21-1 and exfoliated cells
HUI ya-lin,LU Yu-hong,ZHAO Yong. Clinical evaluation of the differentiating diagnosis of 102 patients with pleural effusion by detection of CEA,CYFRA21-1 and exfoliated cells[J]. Journal of Yanan University:Medical Science Edition, 2011, 9(1): 27-28
Authors:HUI ya-lin  LU Yu-hong  ZHAO Yong
Affiliation:HUI ya-lin,LU Yu-hong,ZHAO Yong (Department of Emergency,Armed Police Academy of Engineering,Xian,Shaanxi 710086)
Abstract:Objective To explore the value of carcinoembryonic antigen(CEA) and cytokeratin fragment antigen 21-1(CYFRA21-1)in hydrothorax and serum as well as exfoliated cells in hydrothorax in differential diagnosis of benign and malignant pleural effusion.Methods Measure content of CEA,CYFRA21-1 in hydrothorax and serum of 51 cases with tuberculous and malignant pleural effusion,respectively,and examine pleural effusion cytology concurrently.Results The sensitivity and specificity of CEA and CYFRA21-1 in diagnosis o...
Keywords:CEA  CYFRA21-1  Exfoliated Cells  Diagnosis  
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