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奥硝唑注射液治疗妇产科厌氧菌感染的临床效果
引用本文:遇苏宁,文爱东,辛晓燕,李桂云,吴寅.奥硝唑注射液治疗妇产科厌氧菌感染的临床效果[J].中国新药杂志,2004,13(2):158-160.
作者姓名:遇苏宁  文爱东  辛晓燕  李桂云  吴寅
作者单位:第四军医大学第一附属医院,西安,710032
摘    要:目的:评价奥硝唑氯化钠注射液治疗妇产科厌氧菌感染的临床疗效及安全性.方法:厌氧菌感染患者94例随机分为2组,试验组静滴奥硝唑氯化钠注射液500mg,bid,对照组静滴甲硝唑氯化钠注射液500mg,bid,疗程5d.结果:试验组和对照组临床治愈率分别为72.3%及66.0%(P>0.05);细菌清除率分别为85.0%及81.0%(P>0.05);不良反应发生率分别为6.4%及8.5%(P>0.05).结论:奥硝唑氯化钠注射液治疗妇产科厌氧菌感染安全有效.

关 键 词:奥硝唑  注射注  甲硝唑  妇产科  厌氧菌感染
文章编号:1003-3734(2004)02-0158-03

Clinical effect of ornidazole injection in treatment of anaerobic infections in gynecology
YU Su-ning,WEN Ai-dong,XIN Xiao-yan,LI Gui-yun,WU Yin.Clinical effect of ornidazole injection in treatment of anaerobic infections in gynecology[J].Chinese Journal of New Drugs,2004,13(2):158-160.
Authors:YU Su-ning  WEN Ai-dong  XIN Xiao-yan  LI Gui-yun  WU Yin
Abstract:Objective: To study the safety and efficacy of ornidazole injection in treatment of anaerobic infections in gynecology. Methods: 94 female patients with anaerobic infection were randomly divided to receive twice daily infusion of ornidazole injection 500mg plus normal saline or twice daily infusion of metornidazole injection 500mg plus normal saline for 5d. Results:The total effective rate,bacterial clearance, and incidence of ADR were 72. 3% , 85. 0% , and 6.4% respectively for the active group and 66.0% ,81.0% ,and 8.5% respectively for the control group. Conclusion:Orindazole injection is effective in treatment of anaerobic infections in gynecology.
Keywords:ornidazole  injection  metornidazole  gynecology  anaerobic infection
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