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A novel positive feedback loop involving FASN/ p-ERK1/2/5-LOX/LTB4/FASN sustains high growth of breast cancer cells
Authors:Nan HU  Yu LI  Yu ZHAO  Qi WANG  Jia-cong YOU  Xiao-dong ZHANG  Li-hong YE
Affiliation:[1]Deoartment of Biochemistry, the Key Laboratory of Bioactive Materials, Ministry of Education [2]Department of Cancer Research, KeyLaboratory of Molecular Microbiology and Technology of Ministry of Education, Institute for Molecular Biology and Biochemistry College of Life Sciences, Nankai University, Tianjin 300071, China
Abstract:
Keywords:breast cancer  extracellular signal-regulated kinase  fatty acid synthase  5-1ipoxygenase  leukotriene B4  cell proliferation
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