小肝癌术后早期复发的多因素分析

目的:探讨影响小肝癌术后早期复发的影响因素。方法:回顾性分析2001年1月～2005年12月肿瘤医院收治经病理证实的原发性小肝癌,经手术切除单个结节最大直径≤5 cm或两个结节最大直径之和≤5 cm的小肝癌46例。分析肿瘤大小、手术切缘、术中输血及肿瘤数目等与小肝癌术后无瘤生存期的关系。结果:46例病例中早期肝内复发34例。多因素分析表明肿瘤大小、术中输血是早期复发的独立危险因素。结论:肿瘤大小、手术切缘、术中输血是影响病人术后早期肝内复发的重要因素。积极防治复发将是延长术后无瘤生存期的重点。

Multivariate analysis on factors of early postoperative intrahepatic recurrence for small liver cancer

Objective:To investigate the factors influencing early intrahepatic recurrence after section of small liver cancer.Methods:From January 2001 to December 2005, 46 patients who underwent hepatecto- my for small liver cancer(the maximum diameter 5cm in single nudule or the sum of diameters in double nodule equal to or less than 5 cm)were enrolled for reviewing analysis.SPSS 13.0 for window software was used for statistics.The relation were retrospectively reviewed between tumor size,cutting margins, blood transfusion and tumor-free survival of small liver cancer.Results:Early intrahepatic recurrence oc- curred in 41 of 46 cases.Multivariate analysis showed that tumor size,cutting margins,blood transfusion were independent risk factors.Conclusion:Tumor size,blood transfusion are corelated significantly with early intrahepatic recurrence.Close surveillance and following-up are the keys for prolonging the tumor- free survival time.