| 卵巢恶性肿瘤雌激素受体及孕激素受体的研究 |
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| 引用本文： | 史锦兰 陈萍倩. 卵巢恶性肿瘤雌激素受体及孕激素受体的研究[J]. 中国肿瘤临床, 1994, 21(5): 352-354,363 |
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| 作者姓名： | 史锦兰 陈萍倩 |
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| 作者单位： | 江苏无锡市妇幼保健院 无锡市214002 |
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| 摘 要： | 应用酶联雌二醇（Ｅ２－ＨＲＰ）和酶联孕酮（Ｐｇ－ＨＲＰ）亲和组化法检测卵巢恶性肿瘤雌激素受体和孕激素受体４５例，结果ＥＲ阳性３５例，ＰｇＲ阳性３３例，其阳性检出率依次为７７％和７３％，不同类型肿瘤的受体水平有差异，上皮性癌肿的阳性检出率较转移癌高。检测结果显示：肿瘤分化越好，受体水平也越高，早期癌比晚期癌的ＥＲ，ＰｇＲ受体水平高，受体阳性者术后加用他莫西芬联合化疗治疗，其生存时间较阴性者长，复发亦
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| 关 键 词： | 雌激素 孕激素 受体 卵巢肿瘤 癌 |
Estrogen and Progesterone Receptors in Ovarian Malignant Tumor |
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| Shi Jin-Lan et al Wuxi Maternity and Infant Health Hospital,Wuxi. Estrogen and Progesterone Receptors in Ovarian Malignant Tumor[J]. Chinese Journal of Clinical Oncology, 1994, 21(5): 352-354,363 |
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| Authors: | Shi Jin-Lan et al Wuxi Maternity Infant Health Hospital Wuxi |
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| Abstract: | Using E2-HRP and Pg-HRP immunohistochemical technique in 45 eases of malignant tumor of the o-vary ER and PR were tested with positive rates of 77% and 73% respectively. The ER and PgR levels in epithelial cancer of the ovary were higher than those of other pathologic type ovarian tumors and it was lowest in metastatic tumors. The results also showed that the better the differentiation of the cancer cells the higher of the level of the ER and PgR contentswere. |
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| Keywords: | Cancer of overy Estrogen receptor (ER) Progesterone receptor (PgR) |
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