| 脑瘤的组胺研究及其临床意义 |
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| 引用本文： | 李萍,黄国兰.脑瘤的组胺研究及其临床意义[J].中国肿瘤临床,1994,21(12):926-928. |
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| 作者姓名： | 李萍 黄国兰 |
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| 作者单位： | 天津市神经病学研究所，天津市神经病学研究所，南开大学环境科学系 天津市300052，天津市300052 |
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| 摘 要： | 报告36份脑瘤组织的组胺测定结果,其中包括低恶度及高恶度星形细胞瘤22份,不同亚型脑膜瘤14份;并以10份正常脑组织为对照.结果发现脑瘤组织的组胺含量显著增高,其增高水平与肿瘤的恶性程度明显相关;故认为脑瘤组织的组胺可以作为评估肿瘤恶性程度的生化标志物,而且也为今后进一步研究H_2受体阻断剂治疗脑瘤提供线索及实验依据.
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| 关 键 词： | 脑瘤 组胺 H_2受体阻断剂 |
Determination of Histamine Content in Brain and Brain Tumors |
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| Li Ping et al Tianjin Research Institute of Neurology,Tianjin.Determination of Histamine Content in Brain and Brain Tumors[J].Chinese Journal of Clinical Oncology,1994,21(12):926-928. |
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| Authors: | Li Ping Tianjin Research Institute of Neurology Tianjin |
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| Abstract: | The histamine contents of 36 brain tumors and 10 normal brain tissues were determined. The results showed that histamine level was elevated in all brain tumors and its elevation was significantly correlated with the malignancy of brain tumors. It was concluded that histamine could be used as a biochemical marker in- the evaluation of malignancy of brain tumor. Meanwhile, a clue for the treatment of brain with blockers of H2 receptors provided by the present study warrants further study. |
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| Keywords: | Brain tumor Histamine Blocking agent of H2 receptor |
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