猪脾浸液透析物（PS—DLE）对肿瘤患者红细胞C3b受体活性的影响

用酵母菌花环试验,检测健康成人和肿瘤患者红细胞C_3b受体免疫粘附活性.结果发现PS—DLE对26例健康成人红细胞C_3b受体活性具有激活作用(P<0.01),检测17例肿瘤患者红细胞C_3b受体酵母菌花环率与健康人相比,明显偏低(P<0.01),经PS—DLE(4单位/日)治疗1周后,其红细胞C_3b受体活性明显提高,与治疗前比较相差非常显著(P<0.01).本实验结果表明,肿瘤患者的红细胞免疫功能是处于抑制状态,而PS—DLE可以提高红细胞的免疫功能.

The Effects of Dialyzable Leukocyte Extracts of the Swine Spleen on C3b Receptor and Immune Adhered Activity of Erythrocytes in Patients with Malignant Tumor

The C3b receptor activity of erythrocytes were determined in 26 cases of healthy adults and 17 patients with malignant tumor by the rosette formation rate of red-cell C3b receptor. The Dialyzable Leukocyte Extracts of the Pig Spleen (PS-DLE) markedly improved the C3b receptor activity of erythrocytes in healthy adults (P<0. 01). The C3b receptor activity was markedly decreased in patient with malignant tumor than in healthy adults (P<0. 01). The C3b receptor activity was remarkably increased after PS-DLE treatment as compared with that before the treatment. The results showed that the red cell immunity of malignant tumor patient is inhibited and that the PS-DLE is able to improve red cell immnue function.