| CA50、CA242诊断消化系统恶性肿瘤的临床价值 |
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| 作者姓名： | Huang C Bei L Liu T |
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| 作者单位： | 1. 汕头市第二人民医院汕头 515011
2. 中国医学科学院中国协和医科大学协和医院北京 100730 |
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| 摘 要： | 目的 糖链抗原ＣＡ２４２和ＣＡ５０为近年发现的肿瘤血清学标记物,本工作为探讨ＣＡ５０、ＣＡ２４２在消化道肿瘤中的诊断意义。方法 应用放免法测定１６４例消化系统恶性肿瘤患者和６９例良性疾病患者血清中ＣＡ５０、ＣＡ２４２水平。结果 两种肿瘤标记物很少在良性疾病患者中升高,假阳性ＣＡ５０ ７．３％,ＣＡ２４２ ４．３％。结论 ＣＡ５０和ＣＡ２４２在消化系统恶性肿瘤患者中的总敏感性分别为７０％和６３％,Ｃ
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| 关 键 词： | 糖链抗原 血清肿瘤标记物 诊断 消化道肿瘤 |
| 修稿时间： | 1997年8月20日 |
The clinical value of tumor marker CA50 and CA242 in digestive tract cancer |
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| Huang C,Bei L,Liu T.The clinical value of tumor marker CA50 and CA242 in digestive tract cancer[J].Acta Academiae Medicinae Sinicae,1998,20(4):285-288. |
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| Authors: | Huang C Bei L Liu T |
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| Institution: | 2nd Municipal Hospital of Shan Tou, Shan Tou 515011. |
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| Abstract: | OBJECTIVE: CA50 and CA242 are newly recognized serum tumor marker. This study is to show their value in the diagnosis of digestive tract tumor. METHODS: 164 patients with malignant digestive disease and 69 patients with benign disease were chosen. CA50 and CA242 level of these patients were measured by immunoradiometric assay. RESULTS: The total sensitivity of CA50 and CA242 are 70% and 63% respectively. Two tumor markers rarely elevated in the patients with benign disease (false positive rate CA50 7.3%, CA242 4.3%). High percentage of elevated CA242 level was recorded in the patients with pancreatic and biliary cancers (Sensitivity 79%). Both have low sensitivity in patients with liver carcinoma. CONCLUSIONS: CA50 and CA242 are valuable marker in the diagnosis of digestive tract tumor. |
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