伤痛万应酊治疗急性软组织损伤（气滞血瘀证）的临床疗效观察

目的评价伤痛万应酊治疗急性软组织损伤（气滞血瘀证）的有效性及安全性。方法采用多中心、随机、双盲、安慰剂平行对照的方法将288例急性软组织损伤（气滞血瘀证）患者随机分为治疗组与对照组。治疗组予以伤痛万应酊外擦患处,对照组予以安慰剂外擦患处,用法均为1次3ml,1日5次,疗程为7d。观察患者治疗前后的VAS评分、临床症状、体征的变化。结果①治疗组总有效率为85.21%,对照组总有效率为70.71%,治疗组疗效明显优于对照组（P〈0.01）;②治疗组治疗后的VAS评分较治疗前及对照组均明显下降（P〈0.01）,主症疼痛、压痛较对照组明显改善（P〈0.01）,其余单项症状评分组间差异均无统计学意义（P〉0.05）。结论伤痛万应酊治疗急性软组织损伤（气滞血瘀证）疗效确切、安全。

Clinical Observation of Shangtong Wanying Tincture in Treating Acute Soft Tissue Injury

Objective To evaluate the effectivity and safety of Shangtong Wanying tincture（STWYT）in trea-ting acute soft tissue injury（syndrome of qi stagnation and blood stasis）. Methods 288 patients with acute soft tis- sue injury, adopting multicentre, randomized, double-blind and placebo comparsion method of clinical trial, were randomly divided into the treatment group（treated with STWYT）and the control group（treated with placebo）, 144 cases in each group. Patients in two groups were treated with STWYT or placebo respectively by external applica- tion for 7 days,five times each day,3 ml each time. The change of VAS scores and clinical symptoms before and af-ter the treatment were observed. Results ① The total effective rate was 85.21% （treatment group）vs 70.71% （control group） ,and there was statistical difference between the two groups（P〈0.01）. ②The VAS scores in the treatment group decreased obviously after treatment（P〈0.01）,and the decrease degree was higher than that of control group （P〈0.01）. In addition, the symptoms of pain and tenderness were obviously ameliorated as compared with control group（P〈0.01）. No remarkable differences in the other clinical symptoms were found between the two groups（P〉0.05）. Conclusion Shangtong Wanying tincture was effective and safety for the treatment of acute soft tissue injury.