贝克曼库尔特LH750型血液分析仪血小板相关参数的实验调查和应用探讨

目的 :通过对贝克曼库尔特 L H75 0型血液分析仪的血小板相关参数 (MPV、PCT和 PDW)的调查 ,确定本地区本型号仪器的正常参考范围 ,同时观察异常情况下的相应变化。方法 :调查血小板总数在 10 0× 10 9/ L～ 30 0×10 9/ L的正常结果 2 0 0 0例 ,血小板总数低于 10 0× 10 9/ L的结果 2 0 0例 ,血小板总数 CP(T)高于 30 0× 10 9/ L的结果 2 0 0例。结果 :总数正常组 :MPV均值 7.6 fl(6 .0 3fl～ 9.17fl) ,PCT均值 0 .181% (0 .10 9%～ 0 .2 5 3% ) ,PDW均值 16 .91% (15 .38%～ 18.4 4 % ) :总数低组 :MPV均值 8.73fl,PDW均值 17.5 5 % ,与正常组比较相差非常显著 (P<0 .0 1) ;总数高组 :MPV均值 7.70 fl,PDW均值 16 .5 3% ,与正常组比较相差不明显。结论 :MPV值整体上有随血小板总数减少而增大的趋势 ,PDW值随血小板总数减少而增大的现象尤为明显。在血小板总数减少的病例中 ,同时观察 MPV和PDW的改变可了解大体积血小板产生的大致状况。临床上如把血小板总数、MPV和 PDW三个指标综合观察分析将更加有价值。

Investigation of Plateelet Relevance Parameter by Beckman-Coulter LH 750 Hematology and Its Clinical Application

Objectives To investigate the platelet relevance parameter(MPV、PCT and PDW)by Beckman-Coulter LH 750 hematology analyzer for establishing the reference range of platelet in shantou district,and to observe the changes of platelet relevance parameter in abnormalcondition.Methods lnvestigated 2000 cases of normal platelet (100×109/L~300×109/L)and 200 cases oflow platelet(<100×109/L)and 200 cases high platelet(>300×109/L)by LH 750.Results In 2000 cases of normal platelet,the mean of MPV was 7.61 fl(6.03 fl~9.17 fl),PCT was 0.181 %(0.109 %~0.253 %),PDW was 16.91 %(15.38 %~18.44 %).In 200 cases of low platelet,the mean of MPV was 8.73 fl,PDW was 17.55 %,there was very significant difference between the low platelet group and normal platelet group(P<0.01),In 200 cases of high platelet,the mean of MPV was 7.70 fl,PDW was 16.53 %,no significant difference between the high platelet group and normal platelet group.Conclusions MPV increase with platelet decrease and PDW increase was evident.In cases of low platelet,observe the changes of MPV and PDW can know production about large platelet.The overall analysis of platelet、MPV and PDW is very valuable in clinical application.