| 急性白血病完全缓解期骨髓象的预后意义 |
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| 引用本文： | 姚尔固,林凤茹,张瑞欣,段玉芝,范宏,刘建玲. 急性白血病完全缓解期骨髓象的预后意义[J]. 河北医科大学学报, 1991, 0(4) |
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| 作者姓名： | 姚尔固 林凤茹 张瑞欣 段玉芝 范宏 刘建玲 |
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| 作者单位： | 河北医学院附属二院血液病研究室，河北医学院附属二院血液病研究室，河北医学院附属二院血液病研究室，河北医学院附属二院血液病研究室，河北医学院，河北医学院 进修医师，进修医师 |
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| 摘 要： | 分析124例急性白血病完全缓解期骨髓象表现及其对缓解期的影响。所用参数为增生程度及原始细胞、早幼粒(幼单、幼淋)细胞、有核红细胞、中幼粒细胞以下粒细胞和淋巴细胞的百分数。另有6例用流式细胞仪检测完全缓解期骨髓单个核细胞的DNA含量,以期发现残存白血病细胞及异常DNA含量的预后意义。结果表明,以上参数对缓解期的长短无明显影响。要延长缓解期,坚持缓解后治疗(巩固、维持和强化)极为重要。
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| 关 键 词： | 预后因素 完全缓解 急性白血病 |
PROGNOSTIC SIGNIFICANCE OF MARROW FINDINGS IN ACUTE LEUKEMIA IN COMPLETE REMISSION |
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| Yao Ergu Lin Fengru Zhang Ruixin Duan Yuzhi Fan Hong Liu Jianling Laboratory of Hematology,Second Affiliated Hospital. PROGNOSTIC SIGNIFICANCE OF MARROW FINDINGS IN ACUTE LEUKEMIA IN COMPLETE REMISSION[J]. Journal of Hebei Medical University, 1991, 0(4) |
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| Authors: | Yao Ergu Lin Fengru Zhang Ruixin Duan Yuzhi Fan Hong Liu Jianling Laboratory of Hematology Second Affiliated Hospital |
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| Abstract: | Bone marrow findings at the time of complete remission were analyzed in 124 patients with acute leukemia to determine if some variables were predictive for remission duration. Percentage of blasts, promyelocytes (promonocytes or prolymphocytes), erythroid precursors, granulocytes (myelocytes and more mature cells) and lymphocytes and celluarity in the marrow aspirate were analyzed. In addition, DNA contents were measured by flow cytometry in 6 cases to detect the residual leukemic cells in remission marrow and to identify the prognostic significance of the abnormal DNA contents. The data failed to demonstrate any statistically significant difference in remission duration. In order to prolong the remission duration, we consider that the post-remission therapy including consolidation, intensification and maintenance is of great importance. |
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| Keywords: | prognostic factor complete remission acute leukemia |
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