| 芽孢杆菌生物被膜形成分子调控机制的研究进展 |
| |
| 引用本文： | 许姗姗,刘增智,李文利.芽孢杆菌生物被膜形成分子调控机制的研究进展[J].中国海洋药物,2019,38(5):61-68. |
| |
| 作者姓名： | 许姗姗 刘增智 李文利 |
| |
| 作者单位： | 中国海洋大学海洋药物教育部重点实验室,中国海洋大学海洋药物教育部重点实验室,中国海洋大学海洋药物教育部重点实验室 |
| |
| 基金项目： | 国家自然科学基金(31570032)资助 |
| |
| 摘 要： | 生物被膜是微生物为了适应自然界环境变化而形成的,是微生物一种常见的生存状态。芽孢杆菌在海洋环境中分布广泛,许多菌株能够产生复杂的生物被膜,使得它们在生物防治方面具有巨大的应用潜力。目前关于芽孢杆菌生物被膜的研究主要是以模式菌株枯草芽孢杆菌为研究对象。本文综述了目前对枯草芽孢杆菌形成生物被膜的分子调控机制研究所取得的重要进展,包括Spo0A调控机制,SinR-SlrR开关调节系统,DegS-DegU双组分系统,同时介绍了Abh,Veg,RemA等参与的调控机制。
|
| 关 键 词： | 枯草芽孢杆菌，生物被膜，分子调控机制，调控基因 |
| 收稿时间： | 2019/4/30 0:00:00 |
| 修稿时间： | 2019/5/10 0:00:00 |
Recent Advances on Regulation Mechanisms of Biofilm Formation of Bacillus |
| |
| XU Shan-shan,LIU Zeng-zhi and LI Wen-li.Recent Advances on Regulation Mechanisms of Biofilm Formation of Bacillus[J].Chinese Journal of Marine Drugs,2019,38(5):61-68. |
| |
| Authors: | XU Shan-shan LIU Zeng-zhi and LI Wen-li |
| |
| Institution: | Key Laboratory of Marine Drugs,Ministry Education of China,School of Medicine and Pharmacy,Ocean University of China,Qingdao,Shandong Province 266003;China,Key Laboratory of Marine Drugs,Ministry Education of China,School of Medicine and Pharmacy,Ocean University of China,Qingdao,Shandong Province 266003;China,Key Laboratory of Marine Drugs,Ministry Education of China,School of Medicine and Pharmacy,Ocean University of China,Qingdao,Shandong Province 266003;China |
| |
| Abstract: | Biofilm is a common living state of microorganisms, whose formation is a strategy by which microorganisms survive and adapt to the environmental conditions. Bacillus strains are widely distributed in the marine environment, and some of them can produce complex biofilms, having great potential for application in biological control. At present, the researches on regulation mechanisms of Bacillus biofilm formation mainly focuses on the model strain Bacillus subtilis. This paper reviews the recent progresses in the molecular regulation mechanism of biofilm formation of Bacillus subtilis, involving well-studied Spo0A, SinR-SlrR switch, two-component system DegS-DegU, as well as Abh, Veg and RemA. |
| |
| Keywords: | Bacillus subtilis biofilm molecular regulatory mechanism regulatory gene |
|
| 点击此处可从《中国海洋药物》浏览原始摘要信息 |
| 点击此处可从《中国海洋药物》下载免费的PDF全文 |
|
