| 前列腺癌中非编码RNA与雄激素受体信号间调控的研究进展 |
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| 引用本文： | 周金宝,刘小敏,马中良.前列腺癌中非编码RNA与雄激素受体信号间调控的研究进展[J].转化医学杂志,2019,8(2):65-70. |
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| 作者姓名： | 周金宝 刘小敏 马中良 |
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| 作者单位： | 上海大学生命科学学院,上海大学生命科学学院,上海大学生命科学学院 |
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| 基金项目： | 国家自然科学基金（81601887） |
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| 摘 要： | 雄激素受体（androgen receptor，AR）及其下游信号在前列腺癌的发生发展中发挥着关键性的作用。微小RNA（microRNA，miRNA）和长链非编码RNA（long non-coding RNA，lncRNA）等非编码RNA不仅影响AR信号的调控网络，而且参与前列腺癌的发展进程。作者重点就前列腺癌中miRNA、lncRNA与AR信号间调控网络的研究进展进行综述。
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| 关 键 词： | 前列腺癌 雄激素受体 微小RNA 长链非编码RNA |
Progress of non-coding RNA and androgen receptor signaling in prostate cancer |
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| Authors: | ZHOU Jinbao LIU Xiaomin and MA Zhongliang |
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| Institution: | Laboratory for Non-coding RNA & Cancer, School of Life Sciences, Shanghai University, Shanghai 200444, China,Laboratory for Non-coding RNA & Cancer, School of Life Sciences, Shanghai University, Shanghai 200444, China and Laboratory for Non-coding RNA & Cancer, School of Life Sciences, Shanghai University, Shanghai 200444, China |
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| Abstract: | Androgen receptor (AR) and its related signaling play a critical role in the development of prostate cancer. MicroRNA (miRNA), long non-coding RNA (lncRNA) and other non-coding RNA not only influence the regulatory network of AR signaling but also participate in the development of prostate cancer. This review focuses on the research progress of miRAN, lncRNA and AR signaling in prostate cancer. |
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| Keywords: | Prostate cancer Androgen receptor (AR) MicroRNA (miRNA) Long non-coding RNA (lncRNA) |
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