急性缺血性脑卒中后睡眠障碍与生态学执行功能的相关研究

目的:观察急性缺血性脑卒中后睡眠障碍与生态学执行功能的相关性.方法:选取急性缺血性脑卒中病人103例,根据匹兹堡睡眠质量指数量表评分将病人分为睡眠障碍组与睡眠正常组.采用多导睡眠图(PSG)、生态学执行功能行为评估量表成人版(BRIEF-A)评估睡眠质量和执行功能,比较其组间差异;运用多元逐步回归分析探讨PSG睡眠参数...

Study on the relationship between sleep disturbance and ecological executive function after acute ischemic stroke

ObjectiveTo observe the correlation between sleep disturbance and ecological executive function after acute ischemic stroke.MethodsA total of 103 patients with acute ischemic stroke were selected and divided into sleep disturbance group and normal sleep group according to the Pittsburgh sleep quality index scores.Polysomnography(PSG) and ecological behavior rating inventory of executive function-adult version(BRIEF-A) were used to evaluate sleep quality and executive function, and the difference of which between the two groups was compared.Multiple stepwise regression analysis was applied to explore the correlation between PSG sleep parameters and BRIEF-A scores.ResultsThe total score(GEC), scores of metacognition index(MI) and its factors(organization, planning, working memory, task initiation, task monitoring), and scores of behavior regulation index(BRI) and its factors(conversion, inhibition, self-monitoring, emotional control) of BRIEF-A in sleep disturbance group were higher than those in normal sleep group(P < 0.05 to P < 0.01).Compared with the normal sleep group, the total sleep time(TST) was shortened, the sleep efficiency(SE) decreased, the non-rapid eye movement sleep phase 3(NREM3) decreased, and the rapid eye movement sleep latency(RL), sleep latency(SL), wake-up time after falling asleep, proportion of non-rapid eye movement sleep phase 1 to total sleep time, and proportion of rapid eye movement sleep phase to total sleep time(REM%) increased in the sleep disturbance group(P < 0.05 to P < 0.01).Multiple stepwise linear regression analysis showed that GEC, MI, BRI were negatively correlated with TST and SE(P < 0.05 to P < 0.01), GEC and MI were negatively correlated with the proportion of NREM3 to total sleep time(P < 0.01 and P < 0.05), GEC and MI were significantly positively correlated with REM%(P < 0.01), and GEC was significantly positively correlated with REM%(P < 0.01).ConclusionsPatients with sleep disturbance after acute ischemic stroke have ecological executive function compared with those without sleep disturbance, which are related to sleep parameters in the sleep-wake cycle.