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HBV复制指标之间相互关系的探讨
引用本文:巴秋菊,秦定一,程豪为,赵敏,周灵杰,熊诗松. HBV复制指标之间相互关系的探讨[J]. 郑州大学学报(医学版), 1991, 0(3)
作者姓名:巴秋菊  秦定一  程豪为  赵敏  周灵杰  熊诗松
作者单位:河南省医学科学研究所肝炎研究室(巴秋菊,秦定一,程豪为,赵敏,周灵杰),河南省医学科学研究所肝炎研究室(熊诗松)
摘    要:对44例HBsAg阳性乙型肝炎患者的血清样品进行了HBV—DNA、HBcAg、及HBeAg检测。结果表明;HBeAg与HBV—DNA密切相关,HBeAg阳性血清HBV—DNA检出率为97.30%.统计学分析HBeAg与HBV—DNA两项指标其一致性具有显著意义(0.02>P>0.01);HBeAg与HBeAg两项指标其一致性无显著意义(0.50>P>0.20).HBeAg与HBV—DNA两者之间其一致性无显著意义(P>0.50).在抗—HBe或单项HBsAg阳性血清中仍可见HBV—DNA和HBeAg阳性.提示仍有HBV的复制。

关 键 词:乙型肝炎表面抗原  乙型肝炎“e”抗原  乙型肝炎核心抗原  乙型肝炎病毒脱氧核糖核酸  复制

Investigation of relation among indicators of hepatitis B virus replication
Ba Qiuju,Qin Dingyi,Cheng Haowei,Zhao Min,Zhou Lingjie,Xiong Shisong Henan Institute of Medical Scienes. Investigation of relation among indicators of hepatitis B virus replication[J]. Journal of Zhengzhou University: Med Sci, 1991, 0(3)
Authors:Ba Qiuju  Qin Dingyi  Cheng Haowei  Zhao Min  Zhou Lingjie  Xiong Shisong Henan Institute of Medical Scienes
Affiliation:Ba Qiuju;Qin Dingyi;Cheng Haowei;Zhao Min;Zhou Lingjie;Xiong Shisong Henan Institute of Medical Scienes
Abstract:The sera of 44 cases with positive HBsAg were detected for HBeAg,HBcAg and HBV--DNA. Theresults showed that HBeAg was closely related to HBV--DNA,and that the positive rate of HBV-DNA was 97. 30% in the sera of 37 cases with positive HBeAg. Statistic analysis indicated that theconsistence of HBeAg and HBV--DNA is significant (0. 02>P>0. 01); but that of HBeAg andHBcAg is not significant (0. 50>P>0. 20),nor is that of HBcAg and HBV--DNA (P>0. 50).The fact that HBV--DNA and HBcAg were found in the sera positive for anti--HBe or HBsAg onlysuggests that there may be HBV replication.
Keywords:HBcAg  HBeAg  HBcAg  HBV-DNA  replication
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