Bovine rotavirus strain 678 possesses VP4 of serotype P7[5] specificity |
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| Authors: | T. Nakagomi O. Nakagomi H.-J. Streckert |
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| Affiliation: | Department of Microbiology, Akita University School of Medicine, Akita, Japan, JP
Institut für Hygiene und Mikrobiologie, Abteilung für Medizinische Mikrobiologie und Virologie der Ruhr-Universit?t Bochum, Bochum, Federal Republic of Germany, DE
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| Abstract: | Summary. Bovine rotavirus strain 678 is the first G8 strain of bovine origin but the literature is confusing as to its P type. In this study, two-way cross neutralization between 678 and 0510, a prototype G6P7[5] virus, was shown by plaque-reduction neutralization assays, establishing the P type of 678 as being P7[5]. The P7[5] specificity of 678 VP4 was reinforced by the finding that the VP8* portion of 678 VP4 had the highest amino acid identity with those of P7[5] bovine rotaviruses. Apparent contradiction with previous serological studies relates to intricacy of antigenicity and immunogenicity of UK VP4 in reassortants. Received October 28, 1996 Accepted January 6, 1997 |
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