Glucose and fatty acid kinetics in fasted rats: Effects of previous protein intake |
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Authors: | Gavin T Royle Robert R Wolfe John F Burke |
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Institution: | 1. Department of Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.;2. Shriners Burns Institute, Boston, Massachusetts, USA. |
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Abstract: | Glucose and fatty acid turnover and oxidation were measured in 48 hr fasted adult rats who had been previously fed two isocaloric diets of 5% and 18% protein content for 29 days. Kinetics were investigated with the simultaneous primed constant infusions of 6-3H glucose, U-14C glucose and 1-13C palmitic acid. Plasma glucose concentration and glucose turnover were reduced while plasma fatty acid concentration and turnover were increased in the rats fed the 5% protein diet. The protein:carbohydrate ratio of a previous diet affects both glucose and lipid metabolism in adult rats who are fasted. |
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Keywords: | Address reprint requests to Dr J F Burke Massachusetts General Hospital Boston Massachusetts 02114 |
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