复合茶对实验高脂血症家兔降血脂作用的研究

为观察一种由茶叶、银杏叶、枸杞等组合的复合茶的降血脂作用 ,选取 40只 1.5～ 2 .0 kg家兔 ,随机分为 5组。 组为正常对照组 , 组为高脂血症模型组 , 组为绿茶对照组 , 组为低剂量复合茶组 ; 组为高剂量复合茶组。分别于实验前、实验后 6周末、12周末称重 ,测定血清总胆固醇 (TC)、甘油三酯 (TG)、低密度脂蛋白 (L DL )、高密度脂蛋白 (HDL ) ,并于 12周末处死动物 ,观察心脏、主动脉、肝脏病理改变。结果显示家兔用高脂饲料喂养 12周 ,可形成以高胆固醇血症为主的高脂血症 ;复合茶可明显降低实验动物体重 ,减少脂质在动脉壁和肝脏中的沉积 ,降低血清 TC、TG、L DL,升高血清 HDL,剂量 -效应关系明显。提示复合茶降低实验动物血脂的作用强于绿茶。

Effect of a complex tea on reducing blood lipid in rabbits

In order to observe the effect of a complex tea composed of tea, ginkgo leaf, red koji and fructus lycii on reducing blood lipids in experimental rabbits, 40 rabbits weighted from 1.5 to 2.0 kg were divided randomly into 5 group: (I) normal control group, (II) hyperlipidemia model(positive control), (III) green tea control group, (IV) low dose complex tea group, and (V) high dose complex tea group. Blood triglyceride(TG), cholesterol(TC), lower density lipoprotein(LDL) and high density lipoprotein(HDL) were measured before experiment and 6.12 weeks later. Then the pathological changes of heart, aorta and liver were observed. After 12 weeks of experiment, the results showed that, (1) hyperlipidemia characterized by high TC has been induced by high-fat feeds in group II, (2) the complex tea can reduce body weight and eliminate the lipids deposition in aorta and liver. (3) the complex tea can decrease serum TG, TC,LDL and increase serum HDL in the high complex tea group. The results indicate that the complex tea is more effective than green tea on reducing blood lipids in experimental rabbits.