Drug-induced linear immunoglobulin A bullous disease that clinically mimics toxic epidermal necrolysis |
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Authors: | Mofid M Z Costarangos C Bernstein B Wong L Munster A Nousari H C |
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Affiliation: | Department of Dermatology, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA. |
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Abstract: | Drug-induced linear immunoglobulin A bullous disease is a subepidermal blistering disorder that most commonly occurs after exposure to vancomycin. It can clinically mimic toxic epidermolytic necrolysis. We describe an 87-year-old white woman in whom linear immunoglobulin A bullous disease developed while she was taking vancomycin and phenytoin. A few days after the linear immunoglobulin A bullous disease developed, both medications were discontinued. No new bullae developed, and the eruption completely resolved within 2 weeks. The patient was treated with only topical therapy. |
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