幽门螺杆菌对消化性溃疡穿孔修补后的影响

目的:了解幽门螺杆菌对十二指肠溃疡穿孔单纯修补后溃疡愈合的影响.方法:收集120例穿孔性胃十二指肠溃疡,其中99例(82.5%)为幽门螺杆菌阳性,其中51例为抗HP治疗组,用次橼酸铋120 mg、阿莫西林500 mg和甲硝唑300 mg治疗.48例为单用雷尼替丁治疗组.结果:胃十二指肠穿孔单纯修补后只要消除感染,溃疡复发率就降低.结论:幽门螺杆菌是影响胃十二指肠溃疡穿孔修补后复发的主要因素.

Infiuence of Helicobacter Pylori on Peptic Ulcer Following Perforation Suturing

Objective To understand the influence of Helicobacter pylori(Hp)on gastroduodenal ulcer after-simple suturing of ulcer perforation Methods One hundred and twenty patients with perforated gastroduodenal ulcer 0000 were retrospectively analyzed,of them 99(82.5%) were found Hp positive;51 cases in the anti-Hp group,treated with 120 mg of bismuth subcitrate,500 mg of tetracycline and 300 mg of metronisdazole,48 cases in the control group,treated with ranitidine.Results The ulcer recurrence rate in anti-Hp group was 4.1%,far lower than that(34.0%)in ranitidine control group(P<0.05). Conclusion helicobacter pylori infection is an important factor in the recurrence of peptic ulcer.