The prefrontal-limbic system: development, neuroanatomy, function, and implications for socioemotional development |
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Authors: | Braun Katharina |
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Institution: | Department of Zoology and Developmental Neurobiology, Institute of Biology, Otto von Guericke University Magdeburg, Leipziger Street 44, Building 91, Magdeburg 39120, Germany |
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Abstract: | The knowledge that neonatal emotional experience and associated learning processes are critical in the maturation of prefronto-limbic circuits emphasizes the importance of preterm and neonatal care. The further improvement of care and intervention strategies requires a deeper understanding of epigenetic mechanisms mediating experience-induced synaptic reorganization underlying the emergence of emotional and cognitive behavioral traits. Interdisciplinary research efforts are needed in which pediatricians and developmental biologists and psychologists merge their knowledge, concepts, and methodology. The hope is that the translational relevance of research efforts can be improved through a greater interaction between basic and clinical scientists. |
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Keywords: | Brain development Emotion Learning Memory Amygdala Hippocampus Prenatal stress Neonatal stress |
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