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宣肺止咳合剂提取工艺研究
引用本文:马国平,刘志辉,钱芳,陆超. 宣肺止咳合剂提取工艺研究[J]. 中国中医药信息杂志, 2009, 16(6): 45-46
作者姓名:马国平  刘志辉  钱芳  陆超
作者单位:江苏省中医院药剂科,江苏,南京,210029
摘    要:目的优选宣肺止咳合剂的提取工艺。方法以盐酸麻黄碱含量、正丁醇萃取得率和水提浸膏得率为指标,采用正交试验法,考察水提的工艺条件:加水量、提取时间、提取次数。结果最佳提取工艺为:加8倍量水,煎煮2次,每次60min。结论本研究试验结果可靠,最佳工艺条件适合批量生产。

关 键 词:宣肺止咳合剂  盐酸麻黄碱  正交试验  提取工艺

Study on Extraction Process of Xuanfei Zhike Mixture
Affiliation:MA Guo-ping, LIU Zhi-hui, QIAN Fang, et al (Jiangsu Provincial Hospital of TCM, Nanjing 210029, China)
Abstract:Objective To optimize the extraction process of Xuanfei Zhike Mixture. Methods The preparation process was investigated by 1.9(34) orthogonal design with content of ephedrine hydrochloride, the extraction rate of n-butanol and total extraction as indexes. The main factors influencing the extraction efficiency such as the amount of added water, the time of extraction and times of boiling were investigated. Results The optimum technical condition was as follows: 8 times amount of water, extract 2 times and 60 min for each time. Conclusion The result is reliable. It can be used for mass production.
Keywords:Xuanfei Zhike Mixture  ephedrine hydrochloride  orthogonal test  extraction process
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