女性不孕与支原体、衣原体感染和抗精子抗体的相关性

目的研究支原体(ureaplasma urealyticum UU)、衣原体(chlamydia trachomatic CT)感染与抗精子抗体(antisperm antibodies ASAb)对女性不孕的影响.方法聚合酶链反应(PCR)法和ELISA法分别对128例原发性和195例继发性不孕患者的宫颈分泌物进行UU、CT和ASAb检测,同时选择健康已孕妇女96人作为对照组.结果不孕组UU、CT感染率、ASAb阳性率与对照组比均有显著性差异(P＜0.05);原发不孕组与继发不孕组UU、CT感染率、ASAb阳性率相比无显著性差异(P＞0.05);不孕组中UU、CT感染阳性患者ASAb阳性率明显高于UU、CT阴性患者(P＜0.01).结论女性生殖道UU、CT感染和ASAb与不孕有着密切的相关性,特别是继发性不孕患者尤为显著,且ASAb的产生与CT,UU感染有关.

The relationship of ureaplasma urealyticum and chlamydia trachomatic infection with antisperm antibodies in infertile women

Objective:To study the relationship of ureaplasma urealyticum and chlamydia trachomatic infection with antisperm antibodies in infertile women.Methods:The contrcration test of reproductive tract secretion was performed in 128 primary infertile and 195 secondary infertile with UU and CT polymerase chain reaction(PCR) and antisperm antibodies ELISA.96 health pregnant women assigned as control groups.Results:The statistical analysis showed that the positive rats of UU,CT,ASA in infertile group were higher than those in control group(P<0.05).The positive rats of UU,CT,ASAb showed no difference between primary and secondary infertility(P>0.05).The positive rats of ASAb in infertility patients of UU,CT were higher than those in negative patients(P<0.01).Conclusion:CT,UU and ASA are the main reason that cases the infertility,but they are more significant in secondary infertile.The production of ASAb is related to the infection of CT,UU.