| 赤芝孢子粉三萜化学成分研究 |
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| 引用本文： | 陈若芸,于德泉.赤芝孢子粉三萜化学成分研究[J].药学学报,1991,26(4):267-273. |
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| 作者姓名： | 陈若芸 于德泉 |
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| 作者单位： | 中国医学科学院药物研究所，中国医学科学院药物研究所 北京 100050，北京 100050 |
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| 摘 要： | 自赤芝(Ganoderma lucidum Karst)孢子粉酸性部分分离得到一个新的四环三萜化合物,命名为ganosporeric acid A(1),根据光谱(IR,1HNMR,13CNMR和MS)分析确定其结构为Ⅰ所示。同时还分到四个已知化合物:ganoderic acid B(Ⅱ),ganodefic acid C(Ⅲ),ganoderic acidE(Ⅳ),和ganodermanontriol(Ⅴ)。这些化合物均为首次从赤芝孢子粉中得到。
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| 关 键 词： | 赤芝 孢子粉 Ganosporeric acid A |
| 收稿时间： | 1990-02-20 |
STUDIES ON THE TRITERPENOID CONSTITUENTS OF THE SPORES FROM GANODERMA LUCIDUM KARST |
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| RY Chen and DQ Yu.STUDIES ON THE TRITERPENOID CONSTITUENTS OF THE SPORES FROM GANODERMA LUCIDUM KARST[J].Acta Pharmaceutica Sinica,1991,26(4):267-273. |
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| Authors: | RY Chen and DQ Yu |
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| Institution: | Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing. |
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| Abstract: | Five compounds were isolated from the ether soluble fraction of the spores of Ganoderma lucidum. On the basis of their chemical properties and spectral data (MS, UV, IR, 1H and 13CNMR), they were identified as 3,7,11,12,15,23-hexaoxo-5 alpha-lanosta-8-en-26-oic acid (I), 3 beta,7 beta-dihydroxy-11,15,23-trioxo-5 alpha-lanosta-8-en-26-oic acid (II), 7 beta-hydroxy-3,11,15,23-tetraoxo-5 alpha-lanosta-8-en-26-oic acid (III), 3,7,11,15,23-pentaoxo-5 alpha-lanosta-8-en-26-oic acid (IV), 24,25,26-trihydroxy-5 alpha-lanosta-7,9 (11)-dien-3-one (V), Compound I is a new natural product, named ganosporeric acid A. Compounds II, III, IV and V were obtained for the first time from the spores of Ganoderma lucidum. |
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| Keywords: | Ganoderma lucidum Spores Ganosporeric acid A |
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