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Long-term bowel function,quality of life and sexual function in patients with anorectal malformations treated during the PSARP era
Institution:1. Institution of Women''s and Children''s Health, Uppsala University, Uppsala, Sweden;2. Institution of Surgical Sciences, Uppsala University, Uppsala, Sweden;3. Department of Pediatric Surgery, Akademiska Sjukhuset Uppsala, Sweden;4. Department of Surgery, Akademiska Sjukhuset, Uppsala, Sweden;5. Department of Pediatric Surgery, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden;1. Center for Colorectal and Pelvic Reconstruction, Nationwide Children''s Hospital, Columbus, OH;2. Center for Surgical Outcomes Research, Center for Innovation in Pediatric Practice, Nationwide Children''s Hospital, Columbus, OH;3. Pediatric Urology Department, Nationwide Children''s Hospital, Columbus, OH;4. Children''s Radiological Institute, The Ohio State College of Medicine and Public Health, Columbus, OH;1. Department of Specialist Neonatal and Pediatric Surgery, Great Ormond Street Hospital for Children, Great Ormond Street, WC1N 3JH London, United Kingdom;2. Department of Psychology, Sapienza University of Rome, Via dei Marsi, 78, 00185 Rome, Italy;3. AIMAR-Italian Patients'' and Parents'' Organization for Anorectal Malformation, Via Tripolitania, 211, Rome, Italy;4. SoMA e.V.-German organization for people with ARM/HD, Korbinianplatz 17, D-80807 Munich, Germany;5. Department of Pediatric Surgery, Radboudumc Amalia Children''s Hospital, Postbus 9101, 6500 HB, Nijmegen, The Netherlands;6. National Reference Centre for Rare Diseases on Anorectal Malformations and Rare Pelvic Anomalies (MAREP), Rare Diseases National Network NeuroSphinx, Necker-Enfants Malades Hospital, APHP, René Descartes University, Paris, France;7. \"Vereniging Anusatresie\" Postbus 78, 1270 AB Huizen, The Netherlands;8. Department of Pediatric Surgery, Fondazione IRCCS Ca'' Granda-Ospedale Maggiore Policlinico, Via della Commenda 10, 20122, Milano, Italy;9. Department of Pediatric Surgery, Charité Uniklinik Abt., Kinderchirurgie, Augustenburger Platz, 1, Berlin, Germany;10. Department of Surgery, Charing Cross Hospital, Imperial College Healthcare NHS Trust, Fulham Palace Road, London W6 8RF, United Kingdom
Abstract:Anorectal malformations are an important group of congenital anomalies that vary widely in their anatomical characteristics and complexity. Understanding the long-term functional outcomes after modern treatments, and how these compare to the general population, are essential for ensuring that patients receive optimal, evidence-based care. With increasing appreciation of the wider impact of the illness on patients and their families, minimizing social disability from fecal incontinence and enabling normal social integration from the outset are key management concerns. This review summarizes the current knowledge on the functional outcomes by type of malformation, reflecting on the literature, and our institutional experience over a follow-up period of nearly 30 years.
Keywords:Anorectal malformations  Posterior sagittal anoplasty  Anterior sagittal anorectoplasty  Cutback anoplasty  Rectourethral fistula  Vestibular fistula  Perineal fistula  Anterior anus  Bowel function score  Long-term outcomes
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