Long-term morbidity of congenital diaphragmatic hernia: A plea for standardization |
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| Institution: | 1. Department of Surgery, Division of Pediatric General and Thoracic Surgery, The Hospital for Sick Children, 555 University Ave, M5G 1X8, Toronto, ON, Canada;2. Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children, 555 University Ave, M5G 1X8, Toronto, ON, Canada;3. Department of Pediatrics, Division of Respiratory Medicine, The Hospital for Sick Children, 555 University Ave, M5G 1X8, Toronto, ON, Canada;1. Children''s Hospital Colorado and University of Colorado School of Medicine, Aurora, CO, United States;2. Ann and Robert H. Lurie Children''s Hospital and Feinberg School of Medicine, Northwestern University, Chicago, IL, United States;3. Children''s Mercy Hospital and University of Missouri, Kansas City, MO, United States;4. Children''s Hospital of Pittsburgh and University of Pittsburgh School of Medicine, Pittsburgh, PA, United States;5. Nationwide Children''s Hospital, Columbus, OH, United States;6. Children''s Hospital Association, Overland Park, KS, United States;7. Children''s Healthcare of Atlanta at Egleston, Atlanta, GA, United States;8. Nemours Alfred I. DuPont Hospital for Children, Wilmington, DE, United States;9. Children''s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA, United States;1. Department of Respiratory Medicine, The Children''s Hospital at Westmead, Sydney, Australia;2. Medical School, University of Groningen, Groningen, The Netherlands;3. Discipline of Paediatrics and Child Health, Sydney Medical School, University of Sydney, Sydney, Australia;4. Grace Centre for Newborn Care, The Children''s Hospital at Westmead, Sydney, Australia |
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| Abstract: | Congenital diaphragmatic hernia (CDH) survivors present long-term morbidities in several systems, including the neurodevelopmental, gastrointestinal, pulmonary, and musculoskeletal ones, and CDH long-term sequelae are increasingly being recognized. Due to high co-morbidity, health related quality of life in a significant proportion of CDH patients might be compromised. As a consequence of consciousness on the long-term sequelae of CDH survivors, and their consequences for life, several follow-up programs were brought to life worldwide. In this review, we will summarize the long-term sequelae of CDH survivors, the impact of new treatments, and analyze the consistency of follow-up programs. |
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| Keywords: | Congenital diaphragmatic hernia Outcomes Follow-up Quality of life |
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