Epidemiology and clinical management of tuberculosis in children in Canada |
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| Authors: | Shaun K Morris Anne-Marie Demers Ray Lam Lisa G Pell Ryan JP Giroux Ian Kitai |
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| Institution: | 1.Division of Infectious Diseases, Toronto, Ontario;;2.Centre for Global Child Health, Hospital for Sick Children, Toronto, Ontario;;3.Department of Pediatrics, Faculty of Medicine, University of Toronto, Toronto, Ontario;;4.Department of Microbiology and Immunology and Department of Pediatrics, CHU Sainte-Justine, University of Montreal, Montreal, Quebec;;5.Faculty of Medicine, University of Toronto, Toronto, Ontario |
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| Abstract: | Although often regarded as a foreign disease, latent tuberculosis or tuberculosis disease will be encountered in many clinical situations by the Canadian child health practitioner. There are key differences between tuberculosis in children and adults. In the present article, the changing epidemiology of tuberculosis in children in Canada and around the world, the pathogenesis of infection, diagnostic tests, and clinical management of childhood latent tuberculosis and tuberculosis disease are reviewed. |
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| Keywords: | Children Diagnosis Mycobacterium tuberculosis Pathogenesis Treatment Tuberculosis |
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